Reactome | RUNX1 binds the SOCS4 gene

Schema > Reaction > Entries

authored	[InstanceEdit:8938982] Orlic-Milacic, Marija, 2016-09-14
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8955824] Orlic-Milacic, Marija, 2017-01-13
dbId	8955822
displayName	RUNX1 binds the SOCS4 gene
edited	[InstanceEdit:9005626] Orlic-Milacic, Marija, 2017-05-09
eventOf	[Pathway:R-HSA-8939242] RUNX1 regulates transcription of genes involved in differentiation of keratinocytes - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-8955893] SOCS4 gene expression is inhibited by RUNX1 - Homo sapiens
inferredFrom	[Reaction:R-MMU-8955833] Runx1 binds the Socs4 gene - Mus musculus
input	[Complex:R-HSA-8865330] RUNX1:CBFB [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-8936124] SOCS4 gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:8955594] Defining a tissue stem cell-driven Runx1/Stat3 signalling axis in epithelial cancer
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	RUNX1 binds the SOCS4 gene
output	[Complex:R-HSA-8955821] RUNX1:CBFB:SOCS4 gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-8865320] CBFB binds RUNX1 - Homo sapiens
releaseDate	2017-06-12
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:9005627] Ito, Yoshiaki, 2016-12-20 [InstanceEdit:9005628] Chuang, Linda Shyue Huey, 2016-12-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8955822
summation	[Summation:8955823] Based on studies in mouse keratinocytes, RUNX1, presumably i...

(precedingEvent)	[BlackBoxEvent:R-HSA-8955893] SOCS4 gene expression is inhibited by RUNX1
(hasEvent)	[Pathway:R-HSA-8939242] RUNX1 regulates transcription of genes involved in differentiation of keratinocytes
(inferredTo)	[Reaction:R-MMU-8955833] Runx1 binds the Socs4 gene

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