Reactome | SLC38A9 binds Ragulator:Rag dimers

Schema > Reaction > Entries

SLC38A9 binds Ragulator:Rag dimers Show undefined attributes

authored	[InstanceEdit:8952705] Jassal, Bijay, 2016-12-16
category	binding
compartment	[Compartment:70101] cytosol [Compartment:17938] lysosomal membrane
created	[InstanceEdit:8952705] Jassal, Bijay, 2016-12-16
dbId	8952716
displayName	SLC38A9 binds Ragulator:Rag dimers
edited	[InstanceEdit:8952705] Jassal, Bijay, 2016-12-16
eventOf	[Pathway:R-HSA-165159] MTOR signalling - Homo sapiens
followingEvent	[Reaction:R-HSA-8952726] SLC38A9 transports L-Arg from lysosomal lumen to cytosol - Homo sapiens [Reaction:R-HSA-5653968] Ragulator:Rag dimers:SLC38A9 bind mTORC1 - Homo sapiens
input	[Complex:R-HSA-5653979] Ragulator:RagA,B:GTP:RagC,D:GDP [lysosomal membrane] [EntityWithAccessionedSequence:R-HSA-5215938] SLC38A9 [lysosomal membrane]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8952719] SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1 [LiteratureReference:8952709] Metabolism. Lysosomal amino acid transporter SLC38A9 signals arginine sufficiency to mTORC1 [LiteratureReference:8952699] Amino Acid-Dependent mTORC1 Regulation by the Lysosomal Membrane Protein SLC38A9
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	SLC38A9 binds Ragulator:Rag dimers
orthologousEvent	[Reaction:R-GGA-8952716] SLC38A9 binds Ragulator:Rag dimers - Gallus gallus [Reaction:R-DRE-8952716] SLC38A9 binds Ragulator:Rag dimers - Danio rerio [Reaction:R-SSC-8952716] SLC38A9 binds Ragulator:Rag dimers - Sus scrofa [Reaction:R-BTA-8952716] SLC38A9 binds Ragulator:Rag dimers - Bos taurus [Reaction:R-CFA-8952716] SLC38A9 binds Ragulator:Rag dimers - Canis familiaris [Reaction:R-RNO-8952716] SLC38A9 binds Ragulator:Rag dimers - Rattus norvegicus [Reaction:R-MMU-8952716] SLC38A9 binds Ragulator:Rag dimers - Mus musculus
output	[Complex:R-HSA-8952725] Ragulator:RagA,B:GTP:RagC,D:GDP:SLC38A9 [lysosomal membrane]
precedingEvent	[Reaction:R-HSA-5653974] Ragulator binds Rag dimers - Homo sapiens
releaseDate	2017-03-27
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8955387] D'Eustachio, Peter, 2017-01-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8952716
summation	[Summation:8952734] The sodium-coupled neutral amino acid transporter 9 (SLC38A9...

Referrals

(precedingEvent)	[Reaction:R-HSA-8952726] SLC38A9 transports L-Arg from lysosomal lumen to cytosol [Reaction:R-HSA-5653968] Ragulator:Rag dimers:SLC38A9 bind mTORC1
(hasEvent)	[Pathway:R-HSA-165159] MTOR signalling