Reactome | NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm]

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NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
consumedByEvent	[Reaction:R-HSA-8956045] COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex - Homo sapiens
created	[InstanceEdit:8952583] Rothfels, Karen, 2016-12-15
dbId	8952585
displayName	NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm]
hasComponent	[Complex:R-HSA-8955650] COMMDs:CCDC22 [nucleoplasm] [CandidateSet:R-HSA-8952551] DCUN1D1,2,4,5 [nucleoplasm] [Complex:R-HSA-8952584] NEDD8-CRL4 E3 ligase complex [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Mus musculus [Complex:R-RNO-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Canis familiaris [Complex:R-BTA-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Bos taurus [Complex:R-SSC-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Sus scrofa [Complex:R-DRE-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Danio rerio [Complex:R-XTR-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Gallus gallus [Complex:R-DME-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - Dictyostelium discoideum
isChimeric	false
maxDepth	4
modified	[InstanceEdit:8979797] Rothfels, Karen, 2017-02-27
name	NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5
producedByEvent	[Reaction:R-HSA-8952638] AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8952585
updateTrackers	[UpdateTracker:9903271] Update Tracker - [Complex:8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - v80:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9903271] Update Tracker - [Complex:8952585] NEDD8-CRL4 E3 ubiquitin ligase:COMMDs:CCDC22:DCUN1D1,2,4,5 [nucleoplasm] - v80:[updateContainedComponent]
(output)	[Reaction:R-HSA-8952638] AcM-UBE2M transfers NEDD8 to CRL4 E3 ubiquitin ligase complex
(input)	[Reaction:R-HSA-8956045] COP9 signalosome deneddylates nuclear CRL4 E3 ubiquitin ligase complex

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