JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4

authored
catalystActivity
catalystActivityReference [CatalystActivityReference:9643690] transmembrane receptor protein tyrosine kinase activity of IL35:IL6ST:p-JAK1:IL12RB2:p-JAK2:STAT1:STAT4 [plasma membrane] The composition and signaling of the IL-35 receptor are unconventional
category omitted
compartment
created [InstanceEdit:8950688] Duenas, Corina, 2016-12-02
dbId 8950453
displayName JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4
edited
eventOf
followingEvent
input
isChimeric false
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name
  • JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4
orthologousEvent
output
precedingEvent
releaseDate 2017-09-12
reviewStatus [ReviewStatus:9821382] five stars
reviewed
schemaClass BlackBoxEvent
species
stId R-HSA-8950453
summation
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