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Schema
>
BlackBoxEvent
>
Entries
AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU
Show undefined attributes
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authored
[InstanceEdit:8949670] May, Bruce, 2016-11-28
catalystActivity
[CatalystActivity:8949658] metalloendopeptidase activity of C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane]
catalystActivityReference
[CatalystActivityReference:9643810] metalloendopeptidase activity of C2orf47:AFG3L2:SPG7:PHB:PHB2 [mitochondrial inner membrane] The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria
category
omitted
compartment
[Compartment:70616] mitochondrial inner membrane
created
[InstanceEdit:8949656] May, Bruce, 2016-11-28
dbId
8949659
displayName
AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU
edited
[InstanceEdit:8949670] May, Bruce, 2016-11-28
eventOf
[Pathway:R-HSA-8949664] Processing of SMDT1 - Homo sapiens
input
[EntityWithAccessionedSequence:R-HSA-8949227] SMDT1 [mitochondrial inner membrane]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:8949654] The m-AAA Protease Associated with Neurodegeneration Limits MCU Activity in Mitochondria
maxDepth
1
modified
[InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name
AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU
orthologousEvent
[BlackBoxEvent:R-CEL-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Caenorhabditis elegans
[BlackBoxEvent:R-DME-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Drosophila melanogaster
[BlackBoxEvent:R-GGA-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Gallus gallus
[BlackBoxEvent:R-DRE-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Danio rerio
[BlackBoxEvent:R-SSC-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Sus scrofa
[BlackBoxEvent:R-BTA-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Bos taurus
[BlackBoxEvent:R-CFA-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Canis familiaris
[BlackBoxEvent:R-RNO-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Rattus norvegicus
[BlackBoxEvent:R-MMU-8949659] AFG3L2 (m-AAA protease) degrades SMDT1 that is not assembled in MCU - Mus musculus
precedingEvent
[Reaction:R-HSA-8949649] PMPCA:PMPCB cleaves the transit peptide of proSMDT1 (proEMRE) - Homo sapiens
releaseDate
2017-03-27
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:8956337] Drago, Ilaria, 2017-01-21
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-8949659
summation
[Summation:8953458] Free SMDT1 (EMRE) that is not complexed with MICU1 and MICU2...
Referrals
(hasEvent)
[Pathway:R-HSA-8949664] Processing of SMDT1
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