Reactome | miR-106 RISC:PTEN mRNA [cytosol]

Schema > Complex > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8944628] Orlic-Milacic, Marija, 2016-11-04
dbId	8944631
displayName	miR-106 RISC:PTEN mRNA [cytosol]
hasComponent	[CandidateSet:R-HSA-8944629] miR-106 RISC [cytosol] [EntityWithAccessionedSequence:R-HSA-2318746] PTEN mRNA [cytosol]
inDisease	false
isChimeric	false
literatureReference	[LiteratureReference:8943351] Identification of the miR-106b~25 microRNA cluster as a proto-oncogenic PTEN-targeting intron that cooperates with its host gene MCM7 in transformation [LiteratureReference:8943446] Coding-independent regulation of the tumor suppressor PTEN by competing endogenous mRNAs
maxDepth	6
modified	[InstanceEdit:8948689] Orlic-Milacic, Marija, 2016-11-15
name	miR-106 RISC:PTEN mRNA
negativelyRegulates	[NegativeGeneExpressionRegulation:R-HSA-8944630] Negative gene expression regulation by 'miR-106 RISC:PTEN mRNA [cytosol]'
producedByEvent	[Reaction:R-HSA-8944632] miR-106 microRNAs bind PTEN mRNA - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8944631

(output)	[Reaction:R-HSA-8944632] miR-106 microRNAs bind PTEN mRNA
(regulator)	[NegativeGeneExpressionRegulation:R-HSA-8944630] Negative gene expression regulation by 'miR-106 RISC:PTEN mRNA [cytosol]'

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