Reactome | 'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm]

Schema > Complex > Entries

compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:8944366] Rothfels, Karen, 2016-11-03
dbId	8944365
displayName	'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm]
hasComponent	[Complex:R-HSA-8944351] 'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-205021] HDAC1 [nucleoplasm]
inDisease	false
isChimeric	false
maxDepth	5
name	'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1
negativelyRegulates	[NegativeGeneExpressionRegulation:R-HSA-5229351] Negative gene expression regulation by ''canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm]'
producedByEvent	[Reaction:R-HSA-4641231] TLE recruits HDAC1 to WNT promoters - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8944365

(regulator)	[NegativeGeneExpressionRegulation:R-HSA-5229351] Negative gene expression regulation by ''canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm]'
(output)	[Reaction:R-HSA-4641231] TLE recruits HDAC1 to WNT promoters

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