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'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm]
Stable Identifier
R-HSA-8944365
Type
Complex
Species
Homo sapiens
Compartment
nucleoplasm
Locations in the PathwayBrowser
Expand all
Signal Transduction (Homo sapiens)
Signaling by WNT (Homo sapiens)
Degradation of beta-catenin by the destruction complex (Homo sapiens)
Repression of WNT target genes (Homo sapiens)
TLE recruits HDAC1 to WNT promoters (Homo sapiens)
'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm] (Homo sapiens)
Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes (Homo sapiens)
'canonical' WNT target genes:TCF/LEF:TLE tetramer:HDAC1 [nucleoplasm] (Homo sapiens)
Participants
components
'canonical' WNT target gene:TCF/LEF:TLE tetramer [nucleoplasm]
(Homo sapiens)
HDAC1 [nucleoplasm]
(Homo sapiens)
Participates
as an output of
TLE recruits HDAC1 to WNT promoters (Homo sapiens)
This entity regulates
Negatively
Transcription of canonical WNT targets is repressed by the TLE:HDAC and TCF/CTBP complexes
(Homo sapiens)
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