Reactome | RNF181 [cytoplasm]

Schema > EntityWithAccessionedSequence > Entries

RNF181 [cytoplasm] Show undefined attributes

compartment	[Compartment:459] cytoplasm
componentOf	[Complex:R-HSA-8939334] RNF181:BCL10:Ub:E2 [cytoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-8939323] RNF181 binds BCL10 and Ubiquitin:E2 - Homo sapiens
created	[InstanceEdit:8939339] May, Bruce, 2016-09-18
dbId	8939317
displayName	RNF181 [cytoplasm]
endCoordinate	153
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-8939317] Rnf181 [cytoplasm] - Mus musculus [EntityWithAccessionedSequence:R-RNO-8939317] Rnf181 [cytoplasm] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-8939317] RNF181 [cytoplasm] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-8939317] RNF181 [cytoplasm] - Bos taurus [EntityWithAccessionedSequence:R-SSC-8939317] RNF181 [cytoplasm] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-8939317] rnf181 [cytoplasm] - Danio rerio [GenomeEncodedEntity:R-XTR-8939317] Ghost homologue of RNF181 [cytoplasm] - Xenopus tropicalis [GenomeEncodedEntity:R-GGA-8939317] Ghost homologue of RNF181 [cytoplasm] - Gallus gallus [EntityWithAccessionedSequence:R-DME-8939317] RNF181 [cytoplasm] - Drosophila melanogaster
literatureReference	[LiteratureReference:8984464] RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin alpha(IIb)beta3
maxDepth	1
modified	[InstanceEdit:8984468] May, Bruce, 2017-04-07
name	RNF181 E3 ubiquitin-protein ligase RNF181 ecNumber6.3.2.-/ecNumber RN181_HUMAN
producedByEvent	[BlackBoxEvent:R-HSA-8939335] RNF181 polyubiquinates BCL10 - Homo sapiens
referenceEntity	[ReferenceGeneProduct:uniprot:Q9P0P0] UniProt:Q9P0P0 RNF181
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8939317
startCoordinate	1
updateTrackers	[UpdateTracker:9897244] Update Tracker - [EntityWithAccessionedSequence:8939317] RNF181 [cytoplasm] - v61:[addLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9897244] Update Tracker - [EntityWithAccessionedSequence:8939317] RNF181 [cytoplasm] - v61:[addLiteratureReference]
(input)	[Reaction:R-HSA-8939323] RNF181 binds BCL10 and Ubiquitin:E2
(output)	[BlackBoxEvent:R-HSA-8939335] RNF181 polyubiquinates BCL10
(hasComponent)	[Complex:R-HSA-8939334] RNF181:BCL10:Ub:E2 [cytoplasm]
(activeUnit)	[CatalystActivity:8939336] ubiquitin protein ligase activity of RNF181:BCL10:Ub:E2 [cytoplasm]

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