Reactome | p21 RAS:GTP:moderate kinase activity BRAF mutants [plasma membrane]

Schema > Complex > Entries

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-8936676] Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize - Homo sapiens
created	[InstanceEdit:8936670] Rothfels, Karen, 2016-08-22
crossReference	[DatabaseIdentifier:12020745] Mondo:0004992
dbId	8936669
disease	[Disease:1500689] cancer
displayName	p21 RAS:GTP:moderate kinase activity BRAF mutants [plasma membrane]
hasComponent	[CandidateSet:R-HSA-6802641] moderate kinase activity BRAF mutants [cytosol] [Complex:R-HSA-167204] RAS:GTP [plasma membrane]
inDisease	true
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	4
name	p21 RAS:GTP:moderate kinase activity BRAF mutants
producedByEvent	[Reaction:R-HSA-6802915] Moderate kinase activity BRAF mutants bind RAS:GTP - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8936669
updateTrackers	[UpdateTracker:9900761] Update Tracker - [Complex:8936669] p21 RAS:GTP:moderate kinase activity BRAF mutants [plasma membrane] - v70:[updateContainedComponent]

(updatedInstance)	[UpdateTracker:9900761] Update Tracker - [Complex:8936669] p21 RAS:GTP:moderate kinase activity BRAF mutants [plasma membrane] - v70:[updateContainedComponent]
(input)	[Reaction:R-HSA-8936676] Moderate kinase activity BRAF mutants:RAS:GTP homo/heterodimerize
(diseaseEntity)	[EntityFunctionalStatus:8936673] gain_of_function of p21 RAS:GTP:moderate kinase activity BRAF mutants [plasma membrane]
(output)	[Reaction:R-HSA-6802915] Moderate kinase activity BRAF mutants bind RAS:GTP

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