Reactome | KLK5 [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:8934782] Jupe, Steve, 2016-08-12
dbId	8934778
displayName	KLK5 [cytosol]
endCoordinate	293
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-SSC-8934778] KLK5 [cytosol] - Sus scrofa
literatureReference	[LiteratureReference:8849610] Purification, molecular cloning, and expression of a human stratum corneum trypsin-like serine protease with possible function in desquamation [LiteratureReference:8849614] Structural basis of the zinc inhibition of human tissue kallikrein 5
markingReferences	[MarkerReference:9728087] KLK5 [cytosol] Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum [MarkerReference:9728022] KLK5 [cytosol] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes
maxDepth	1
memberOf	[DefinedSet:R-HSA-8934797] Cytoplasmic profilaggrin processing proteases [cytosol] - Homo sapiens
modified	[InstanceEdit:8934833] Jupe, Steve, 2016-08-12
name	KLK5 KLK5(67-293) Kallikrein-5 SCTE Stratum corneum tryptic enzyme
referenceEntity	[ReferenceGeneProduct:uniprot:Q9Y337] UniProt:Q9Y337 KLK5
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8934778
startCoordinate	67

(proteinMarker)	[Cell:R-HSA-9855603] corneocyte [Cell:R-HSA-9727357] keratinocyte of granulosum layer of epidermis
(marker)	[MarkerReference:9728087] KLK5 [cytosol] Selective Substrates and Inhibitors for Kallikrein-Related Peptidase 7 (KLK7) Shed Light on KLK Proteolytic Activity in the Stratum Corneum [MarkerReference:9728022] KLK5 [cytosol] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes
(hasMember)	[DefinedSet:R-HSA-8934797] Cytoplasmic profilaggrin processing proteases [cytosol]