Reactome | KLK5 [cytosol] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes

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cell	[Cell:R-HSA-9727357] keratinocyte of granulosum layer of epidermis - Homo sapiens
created	[InstanceEdit:9728024] Orlic-Milacic, Marija, 2021-04-20
dbId	9728022
displayName	KLK5 [cytosol] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes
literatureReference	[LiteratureReference:8934808] Kallikrein-related peptidase 5 functions in proteolytic processing of profilaggrin in cultured human keratinocytes [LiteratureReference:9728045] LEKTI is localized in lamellar granules, separated from KLK5 and KLK7, and is secreted in the extracellular spaces of the superficial stratum granulosum [LiteratureReference:9728059] Keratinocyte-specific mesotrypsin contributes to the desquamation process via kallikrein activation and LEKTI degradation
marker	[EntityWithAccessionedSequence:R-HSA-8934778] KLK5 [cytosol]
modified	[InstanceEdit:9824175] Wu, Guanming, 2023-01-17
schemaClass	MarkerReference

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