Reactome | SLC27A3 ligates CoA-SH to VLCFA

Schema > Reaction > Entries

SLC27A3 ligates CoA-SH to VLCFA Show undefined attributes

authored	[InstanceEdit:8875072] Jassal, Bijay, 2016-06-01
catalystActivity	[CatalystActivity:8875075] very long-chain fatty acid-CoA ligase activity of SLC27A3 [mitochondrial matrix]
category	transition
compartment	[Compartment:5460] mitochondrial matrix
created	[InstanceEdit:8875073] Jassal, Bijay, 2016-06-01
crossReference	[DatabaseIdentifier:12667579] RHEA:54537 [DatabaseIdentifier:9865934] RHEA:54537
dbId	8875077
displayName	SLC27A3 ligates CoA-SH to VLCFA
edited	[InstanceEdit:8875072] Jassal, Bijay, 2016-06-01
eventOf	[Pathway:R-HSA-75876] Synthesis of very long-chain fatty acyl-CoAs - Homo sapiens
inferredFrom	[Reaction:R-MMU-8875095] Slc27a3 ligates CoA to VLCFA - Mus musculus
input	[SimpleEntity:R-ALL-113593] ATP [mitochondrial matrix] [SimpleEntity:R-ALL-29374] CoA-SH [mitochondrial matrix] [SimpleEntity:R-ALL-5696008] VLCFA [mitochondrial matrix]
isChimeric	false
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:5696002] Evidence for 26 distinct acyl-coenzyme A synthetase genes in the human genome [LiteratureReference:8875074] Mouse very long-chain Acyl-CoA synthetase 3/fatty acid transport protein 3 catalyzes fatty acid activation but not fatty acid transport in MA-10 cells
maxDepth	1
modified	[InstanceEdit:9865937] D'Eustachio, Peter, 2024-03-20
name	SLC27A3 ligates CoA-SH to VLCFA a very long-chain fatty acid + ATP + CoA => a very long-chain fatty acyl-CoA + AMP + diphosphate
output	[SimpleEntity:R-ALL-159448] AMP [mitochondrial matrix] [SimpleEntity:R-ALL-159450] PPi [mitochondrial matrix] [SimpleEntity:R-ALL-5696003] VLCFA-CoA [mitochondrial matrix]
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8879141] D'Eustachio, Peter, 2016-07-15
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-8875077
summation	[Summation:8875079] Acyl-coenzyme A synthetases catalyse the activation of fatty...

Referrals

(hasEvent)	[Pathway:R-HSA-75876] Synthesis of very long-chain fatty acyl-CoAs
(inferredTo)	[Reaction:R-MMU-8875095] Slc27a3 ligates CoA to VLCFA

Cite Us!