Reactome | EGFR gene expression is stimulated by TFAP2C

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EGFR gene expression is stimulated by TFAP2C Show undefined attributes

authored	[InstanceEdit:8864334] Orlic-Milacic, Marija, 2016-03-14
category	omitted
compartment	[Compartment:7660] nucleoplasm [Compartment:876] plasma membrane
created	[InstanceEdit:8874791] Orlic-Milacic, Marija, 2016-05-27
dbId	8874797
displayName	EGFR gene expression is stimulated by TFAP2C
edited	[InstanceEdit:8864334] Orlic-Milacic, Marija, 2016-03-14
eventOf	[Pathway:R-HSA-8866910] TFAP2 (AP-2) family regulates transcription of growth factors and their receptors - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-8874800] EGFR gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:8874801] The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis [LiteratureReference:8874784] EGFR Is Regulated by TFAP2C in Luminal Breast Cancer and Is a Target for Vandetanib
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	EGFR gene expression is stimulated by TFAP2C
output	[EntityWithAccessionedSequence:R-HSA-179837] EGFR [plasma membrane]
precedingEvent	[Reaction:R-HSA-8874789] TFAP2C homodimer binds the EGFR gene promoter - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-8874804] Positive gene expression regulation by 'TFAP2C homodimer:EGFR gene [nucleoplasm]'
regulationReference	[RegulationReference:9642471] Positive gene expression regulation by 'TFAP2C homodimer:EGFR gene [nucleoplasm]' The role of Tcfap2c in tumorigenesis and cancer growth in an activated Neu model of mammary carcinogenesis
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8874793] Bogachek, Maria V, 2016-05-17 [InstanceEdit:8874798] Weigel, Ronald J, 2016-05-17
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-8874797
summation	[Summation:8874806] Binding of TFAP2C homodimers to the EGFR gene promoter regio...

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(hasEvent)

[Pathway:R-HSA-8866910] TFAP2 (AP-2) family regulates transcription of growth factors and their receptors

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