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Schema
>
BlackBoxEvent
>
Entries
COP9 and TOR1 deneddylate STON2
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authored
[InstanceEdit:8870660] Rothfels, Karen, 2016-05-10
catalystActivity
[CatalystActivity:8863732] deNEDDylase activity of NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
category
omitted
compartment
[Compartment:70101] cytosol
created
[InstanceEdit:8863722] Rothfels, Karen, 2016-03-09
dbId
8863723
displayName
COP9 and TOR1 deneddylate STON2
edited
[InstanceEdit:8870660] Rothfels, Karen, 2016-05-10
eventOf
[Pathway:R-HSA-8856825] Cargo recognition for clathrin-mediated endocytosis - Homo sapiens
input
[Complex:R-HSA-8863731] NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:8863577] CSN complex controls the stability of selected synaptic proteins via a torsinA-dependent process
maxDepth
1
modified
[InstanceEdit:10996769] Weiser, Joel, 2026-03-16
name
COP9 and TOR1 deneddylate STON2
orthologousEvent
[BlackBoxEvent:R-DDI-8863723] COP9 and TOR1 deneddylate STON2 - Dictyostelium discoideum
[BlackBoxEvent:R-CEL-8863723] COP9 and TOR1 deneddylate STON2 - Caenorhabditis elegans
[BlackBoxEvent:R-DME-8863723] COP9 and TOR1 deneddylate STON2 - Drosophila melanogaster
[BlackBoxEvent:R-GGA-8863723] COP9 and TOR1 deneddylate STON2 - Gallus gallus
[BlackBoxEvent:R-DRE-8863723] COP9 and TOR1 deneddylate STON2 - Danio rerio
[BlackBoxEvent:R-SSC-8863723] COP9 and TOR1 deneddylate STON2 - Sus scrofa
[BlackBoxEvent:R-BTA-8863723] COP9 and TOR1 deneddylate STON2 - Bos taurus
[BlackBoxEvent:R-CFA-8863723] COP9 and TOR1 deneddylate STON2 - Canis familiaris
[BlackBoxEvent:R-RNO-8863723] COP9 and TOR1 deneddylate STON2 - Rattus norvegicus
[BlackBoxEvent:R-MMU-8863723] COP9 and TOR1 deneddylate STON2 - Mus musculus
output
[Complex:R-HSA-416968] COP9 [cytosol]
[EntityWithAccessionedSequence:R-HSA-5690794] NEDD8(1-81) [cytosol]
[CandidateSet:R-HSA-8862880] STON2,1 [cytosol]
[CandidateSet:R-HSA-8863573] TOR1 hexamer [cytosol]
precedingEvent
[Reaction:R-HSA-8863721] NEDD8-STON binds TOR1 hexamer and COP9 complex - Homo sapiens
releaseDate
2016-06-15
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:8870617] Antonescu, Costin N, 2016-05-10
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-8863723
summation
[Summation:8863724] Deneddylation of STON2 by TOR1A and the COP9 signalosome sta...
Referrals
(hasEvent)
[Pathway:R-HSA-8856825] Cargo recognition for clathrin-mediated endocytosis
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