Deneddylation of STON2 by TOR1A and the COP9 signalosome stabilize the protein, allowing it to function in the endocytosis of cargo such as the SYT proteins (Granata et al, 2011).
Granata, A, Koo, SJ, Haucke, V, Schiavo, G, Warner, TT
NEDD8-specific protease activity of NEDD8-STONs:TOR1 hexamer:COP9 [cytosol]
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