Reactome | HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane]

Schema > Complex > Entries

HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:8857578] protein tyrosine kinase activity of HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-8857577] LINC01139 facilitates PTK6 autophosphorylation - Homo sapiens
created	[InstanceEdit:8857564] Orlic-Milacic, Marija, 2016-02-15
dbId	8857567
displayName	HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane]
hasComponent	[Complex:R-HSA-8857556] HBEGF:EGFR:p-Y525-GPNMB [plasma membrane] [EntityWithAccessionedSequence:R-HSA-8857566] LINC01139 [cytosol] [EntityWithAccessionedSequence:R-HSA-5661173] LRRK2 [cytosol] [EntityWithAccessionedSequence:R-HSA-8848000] PTK6 [cytosol]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] - Mus musculus [Complex:R-RNO-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] - Rattus norvegicus [Complex:R-BTA-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] - Bos taurus [Complex:R-SSC-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] - Sus scrofa [Complex:R-DRE-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] - Danio rerio [Complex:R-XTR-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-8857567] HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:8857527] The LINK-A lncRNA activates normoxic HIF1? signalling in triple-negative breast cancer
maxDepth	4
modified	[InstanceEdit:8857579] Orlic-Milacic, Marija, 2016-02-15
name	HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2
producedByEvent	[Reaction:R-HSA-8857565] Phosphorylated GPNMB recruits PTK6 and LRRK2 in the presence of LINC01139 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-8857567

Referrals

(output)	[Reaction:R-HSA-8857565] Phosphorylated GPNMB recruits PTK6 and LRRK2 in the presence of LINC01139
(input)	[Reaction:R-HSA-8857577] LINC01139 facilitates PTK6 autophosphorylation
(physicalEntity)	[CatalystActivity:8857578] protein tyrosine kinase activity of HBEGF:EGFR:p-Y525-GPNMB:LINC01139:PTK6:LRRK2 [plasma membrane]

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