Reactome | FGFR1(22-763):TACC1(571-805) fusion [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8853169] FGFR1(22-763):TACC1(571-805) fusion dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853169] FGFR1(22-763):TACC1(571-805) fusion dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:8853240] Rothfels, Karen, 2016-01-21
crossReference	[DatabaseIdentifier:12020790] Mondo:0018177 [DatabaseIdentifier:8853120] COSMIC:COSF1362
dbId	8853241
disease	[Disease:1247632] glioblastoma
displayName	FGFR1(22-763):TACC1(571-805) fusion [plasma membrane]
endCoordinate	763
hasModifiedResidue	[FragmentInsertionModification:8853111] Insertion of residues 571 to 805 at 764 from UniProt:O75410 TACC1
inDisease	true
literatureReference	[LiteratureReference:8853053] Transforming fusions of FGFR and TACC genes in human glioblastoma
maxDepth	1
memberOf	[CandidateSet:R-HSA-8853277] plasma membrane FGFR1 fusions [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9962055] Matthews, Lisa, 2025-07-30
name	FGFR1(22-763):TACC1(571-805) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:P11362] UniProt:P11362 FGFR1
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8853241
startCoordinate	22
updateTrackers	[UpdateTracker:9964971] Update Tracker - [EntityWithAccessionedSequence:8853241] FGFR1(22-763):TACC1(571-805) fusion [plasma membrane] - v94:[add_removeDisease]

(updatedInstance)	[UpdateTracker:9964971] Update Tracker - [EntityWithAccessionedSequence:8853241] FGFR1(22-763):TACC1(571-805) fusion [plasma membrane] - v94:[add_removeDisease]
(hasMember)	[CandidateSet:R-HSA-8853277] plasma membrane FGFR1 fusions [plasma membrane]
(hasComponent)	[Complex:R-HSA-8853169] FGFR1(22-763):TACC1(571-805) fusion dimer [plasma membrane]

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