Reactome | p-4Y-FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]

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p-4Y-FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-8853211] p-4Y FGFR3(23-760)-TACC3(647-838) dimer [plasma membrane] - Homo sapiens [Complex:R-HSA-8853211] p-4Y FGFR3(23-760)-TACC3(647-838) dimer [plasma membrane] - Homo sapiens
created	[InstanceEdit:8853143] Rothfels, Karen, 2016-01-21
crossReference	[DatabaseIdentifier:12021028] Mondo:0004986
dbId	8853155
disease	[Disease:1493885] bladder carcinoma
displayName	p-4Y-FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane]
endCoordinate	760
hasModifiedResidue	[FragmentInsertionModification:8853102] Insertion of residues 647 to 838 at 761 from UniProt:Q9Y6A5 TACC3 [ModifiedResidue:8853094] O4'-phospho-L-tyrosine at 577 [ModifiedResidue:8853087] O4'-phospho-L-tyrosine at 647 [ModifiedResidue:8853089] O4'-phospho-L-tyrosine at 648 [ModifiedResidue:8853095] O4'-phospho-L-tyrosine at 724
inDisease	true
literatureReference	[LiteratureReference:8852972] Identification of targetable FGFR gene fusions in diverse cancers [LiteratureReference:8852986] Oncogenic FGFR3 gene fusions in bladder cancer
maxDepth	1
modified	[InstanceEdit:9832248] Orlic-Milacic, Marija, 2023-03-29
name	p-4Y-FGFR3(23-760)-TACC3(647-838) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:P22607] UniProt:P22607 FGFR3
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-8853155
startCoordinate	23
updateTrackers	[UpdateTracker:9905622] Update Tracker - [EntityWithAccessionedSequence:8853155] p-4Y-FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] - v85:[modifyEndCoordinate, modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9905622] Update Tracker - [EntityWithAccessionedSequence:8853155] p-4Y-FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] - v85:[modifyEndCoordinate, modifyName]
(hasComponent)	[Complex:R-HSA-8853211] p-4Y FGFR3(23-760)-TACC3(647-838) dimer [plasma membrane]

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