Reactome | IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane]

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IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:873925] protein tyrosine kinase activity of IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-877308] Dephosphorylation of JAKs by PTPs - Homo sapiens [Reaction:R-HSA-9732729] Activated JAK1 binds RAF1 - Homo sapiens [Reaction:R-HSA-873924] Phosphorylation of IFNGR1 by JAK kinases - Homo sapiens
created	[InstanceEdit:873801] Garapati, P V, 2010-06-08
dbId	873820
displayName	IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane]
hasComponent	[Complex:R-HSA-873823] IFNG dimer [extracellular region] [Complex:R-HSA-873800] IFNGR complex with p-JAK [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol [Compartment:984] extracellular region
inferredTo	[Complex:R-MMU-873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - Mus musculus [Complex:R-RNO-873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - Canis familiaris [Complex:R-BTA-873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - Bos taurus [Complex:R-SSC-873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - Sus scrofa [Complex:R-DRE-873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - Danio rerio [Complex:R-GGA-873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - Gallus gallus
isChimeric	false
maxDepth	4
name	IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2
positivelyRegulates	[PositiveRegulation:9737539] Positive regulation by 'IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane]'
producedByEvent	[Reaction:R-HSA-873918] Transphosphorylation of JAK1 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-873820
updateTrackers	[UpdateTracker:9901225] Update Tracker - [Complex:873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - v73:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9901225] Update Tracker - [Complex:873820] IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane] - v73:[updateContainedComponent]
(input)	[Reaction:R-HSA-877308] Dephosphorylation of JAKs by PTPs [Reaction:R-HSA-9732729] Activated JAK1 binds RAF1 [Reaction:R-HSA-873924] Phosphorylation of IFNGR1 by JAK kinases
(regulator)	[PositiveRegulation:9737539] Positive regulation by 'IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane]'
(output)	[Reaction:R-HSA-873918] Transphosphorylation of JAK1
(physicalEntity)	[CatalystActivity:873925] protein tyrosine kinase activity of IFNG:IFNGR1:p-JAK1:IFNGR2:p-JAK2 [plasma membrane]

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