Reactome | IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane]

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IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-9678548] IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9678561] IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors - Homo sapiens [Reaction:R-HSA-873926] IFNG dimer binds IFNGR - Homo sapiens
created	[InstanceEdit:873801] Garapati, P V, 2010-06-08
dbId	873810
displayName	IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane]
hasComponent	2 × [Complex:R-HSA-873803] IFNGR1:JAK1 [plasma membrane] 2 × [Complex:R-HSA-873808] IFNGR2:JAK2 [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
inferredTo	[Complex:R-MMU-873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - Mus musculus [Complex:R-RNO-873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - Canis familiaris [Complex:R-BTA-873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - Bos taurus [Complex:R-SSC-873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - Sus scrofa [Complex:R-DRE-873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - Danio rerio [Complex:R-XTR-873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - Gallus gallus
isChimeric	false
literatureReference	[LiteratureReference:873818] Preassembly and ligand-induced restructuring of the chains of the IFN-gamma receptor complex: the roles of Jak kinases, Stat1 and the receptor chains [LiteratureReference:873815] Seeing the light: preassembly and ligand-induced changes of the interferon gamma receptor complex in cells
maxDepth	3
modified	[InstanceEdit:9691247] Jassal, Bijay, 2020-06-10
name	IFNGR1:JAK1:INFGR2:JAK2
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-873810
updateTrackers	[UpdateTracker:9901602] Update Tracker - [Complex:873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - v74:[modifyName]

Referrals

(updatedInstance)	[UpdateTracker:9901602] Update Tracker - [Complex:873810] IFNGR1:JAK1:INFGR2:JAK2 [plasma membrane] - v74:[modifyName]
(hasComponent)	[Complex:R-HSA-9678548] IFNGR1:JAK1:INFGR2:JAK2:JAK1,2 inhibitors [plasma membrane] [Complex:R-HSA-873829] IFNG:IFNGR1:JAK1:IFNGR2:JAK2 [plasma membrane]
(input)	[Reaction:R-HSA-9678561] IFNGR1:JAK1:INFGR2:JAK2 binds JAK1,2 inhibitors [Reaction:R-HSA-873926] IFNG dimer binds IFNGR

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