Reactome | NTP Binds Active Site of RNA Polymerase II

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NTP Binds Active Site of RNA Polymerase II Show undefined attributes

category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
dbId	75861
displayName	NTP Binds Active Site of RNA Polymerase II
eventOf	[Pathway:R-HSA-75953] RNA Polymerase II Transcription Initiation - Homo sapiens
followingEvent	[Reaction:R-HSA-75866] Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP - Homo sapiens
input	2 × [SimpleEntity:R-ALL-9757634] NTP [nucleoplasm] [Complex:R-HSA-109876] pol II open pre-initiation complex [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation.
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	NTP Binds Active Site of RNA Polymerase II
orthologousEvent	[Reaction:R-HSA-167118] NTP binds active site of RNA Polymerase II in HIV-1 open pre-initiation complex - Homo sapiens [Reaction:R-SCE-75861] NTP Binds Active Site of RNA Polymerase II - Saccharomyces cerevisiae [Reaction:R-SPO-75861] NTP Binds Active Site of RNA Polymerase II - Schizosaccharomyces pombe [Reaction:R-DDI-75861] NTP Binds Active Site of RNA Polymerase II - Dictyostelium discoideum [Reaction:R-CEL-75861] NTP Binds Active Site of RNA Polymerase II - Caenorhabditis elegans [Reaction:R-DME-75861] NTP Binds Active Site of RNA Polymerase II - Drosophila melanogaster [Reaction:R-GGA-75861] NTP Binds Active Site of RNA Polymerase II - Gallus gallus [Reaction:R-XTR-75861] NTP Binds Active Site of RNA Polymerase II - Xenopus tropicalis [Reaction:R-SSC-75861] NTP Binds Active Site of RNA Polymerase II - Sus scrofa [Reaction:R-BTA-75861] NTP Binds Active Site of RNA Polymerase II - Bos taurus [Reaction:R-CFA-75861] NTP Binds Active Site of RNA Polymerase II - Canis familiaris [Reaction:R-RNO-75861] NTP Binds Active Site of RNA Polymerase II - Rattus norvegicus [Reaction:R-MMU-75861] NTP Binds Active Site of RNA Polymerase II - Mus musculus
output	[Complex:R-HSA-83551] Pol II initiation complex [nucleoplasm]
precedingEvent	[Reaction:R-HSA-75949] RNA Polymerase II Promoter Opening: First Transition - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-75861
summation	[Summation:178999] At the beginning of this reaction, 1 molecule of 'pol II ope...

Referrals

(hasEvent)	[Pathway:R-HSA-75953] RNA Polymerase II Transcription Initiation
(precedingEvent)	[Reaction:R-HSA-75866] Nucleophillic Attack by 3'-hydroxyl Oxygen of nascent transcript on the Alpha Phosphate of NTP