Reactome | RNA Polymerase II Promoter Opening: First Transition

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RNA Polymerase II Promoter Opening: First Transition Show undefined attributes

authored	[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
catalystActivity	[CatalystActivity:109879] 3'-5' DNA helicase activity of TFIIH [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:75951] Timmers, H. T. M., 2003-09-11 07:42:30
dbId	75949
displayName	RNA Polymerase II Promoter Opening: First Transition
edited	[InstanceEdit:165073] Joshi-Tope, G, 0000-00-00 00:00:00
eventOf	[Pathway:R-HSA-76042] RNA Polymerase II Transcription Initiation And Promoter Clearance - Homo sapiens
followingEvent	[Reaction:R-HSA-75862] Fall Back to Closed Pre-initiation Complex - Homo sapiens [Reaction:R-HSA-75861] NTP Binds Active Site of RNA Polymerase II - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-HSA-109635] pol II closed pre-initiation complex [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:111269] Polymerase II promoter activation: closed complex formation and ATP-driven start site opening. [LiteratureReference:110387] Three transitions in the RNA polymerase II transcription complex during initiation. [LiteratureReference:110388] Transcription factors IIE and IIH and ATP hydrolysis direct promoter clearance by RNA polymerase II. [LiteratureReference:111270] DNA topology and a minimal set of basal factors for transcription by RNA polymerase II. [LiteratureReference:111271] Peeling by binding or twisting by cranking: models for promoter opening and transcription initiation by RNA polymerase II. [LiteratureReference:110385] The general transcription factors of RNA polymerase II. [LiteratureReference:111272] Reconstitution of the transcription factor TFIIH: assignment of functions for the three enzymatic subunits, XPB, XPD, and cdk7 [LiteratureReference:111273] Mechanism of RNA polymerase II--specific initiation of transcription in vitro: ATP requirement and uncapped runoff transcripts.
modified	[InstanceEdit:10901498] Wright, Adam, 2024-03-08
name	RNA Polymerase II Promoter Opening: First Transition
orthologousEvent	[Reaction:R-HSA-167097] HIV Promoter Opening: First Transition - Homo sapiens [Reaction:R-SCE-75949] RNA Polymerase II Promoter Opening: First Transition - Saccharomyces cerevisiae [Reaction:R-SPO-75949] RNA Polymerase II Promoter Opening: First Transition - Schizosaccharomyces pombe [Reaction:R-DDI-75949] RNA Polymerase II Promoter Opening: First Transition - Dictyostelium discoideum [Reaction:R-CEL-75949] RNA Polymerase II Promoter Opening: First Transition - Caenorhabditis elegans [Reaction:R-DME-75949] RNA Polymerase II Promoter Opening: First Transition - Drosophila melanogaster [Reaction:R-GGA-75949] RNA Polymerase II Promoter Opening: First Transition - Gallus gallus [Reaction:R-XTR-75949] RNA Polymerase II Promoter Opening: First Transition - Xenopus tropicalis [Reaction:R-SSC-75949] RNA Polymerase II Promoter Opening: First Transition - Sus scrofa [Reaction:R-BTA-75949] RNA Polymerase II Promoter Opening: First Transition - Bos taurus [Reaction:R-CFA-75949] RNA Polymerase II Promoter Opening: First Transition - Canis familiaris [Reaction:R-RNO-75949] RNA Polymerase II Promoter Opening: First Transition - Rattus norvegicus [Reaction:R-MMU-75949] RNA Polymerase II Promoter Opening: First Transition - Mus musculus
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [SimpleEntity:R-ALL-113550] Pi [nucleoplasm] [Complex:R-HSA-109876] pol II open pre-initiation complex [nucleoplasm]
precedingEvent	[Reaction:R-HSA-109639] Formation of the closed pre-initiation complex - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-75949
summation	[Summation:75950] After assembly of the complete RNA polymerase II-preinitiati...

Referrals

(hasEvent)	[Pathway:R-HSA-76042] RNA Polymerase II Transcription Initiation And Promoter Clearance
(precedingEvent)	[Reaction:R-HSA-75862] Fall Back to Closed Pre-initiation Complex [Reaction:R-HSA-75861] NTP Binds Active Site of RNA Polymerase II

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