Reactome | Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box

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Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box Show undefined attributes

authored	[InstanceEdit:73851] Comai, L, 2003-07-03 17:13:29
category	dissociation
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:73861] Comai, L, 2003-07-03 17:28:24
dbId	74992
displayName	Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box
edited	[InstanceEdit:165085] Gillespie, ME, 0000-00-00 00:00:00
eventOf	[Pathway:R-HSA-73863] RNA Polymerase I Transcription Termination - Homo sapiens
figure	[Figure:75836] /figures/PolI_txn_term_diss.jpg
followingEvent	[BlackBoxEvent:R-HSA-6791227] 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA - Homo sapiens [Reaction:R-HSA-6790907] Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides - Homo sapiens [Reaction:R-HSA-6790905] Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA - Homo sapiens
input	[Complex:R-HSA-74982] PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:74998] Cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes.
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box
output	[EntityWithAccessionedSequence:R-HSA-74978] nascent pre-rRNA transcript [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-74981] PTRF [nucleoplasm] [Complex:R-HSA-73717] RNA Polymerase I promoter escape complex [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-74974] TTF1 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-74993] PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-74992
summation	[Summation:75000] PTRF binds the quaternary complex and mediates the dissociat...

Referrals

(precedingEvent)	[BlackBoxEvent:R-HSA-6791227] 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA [Reaction:R-HSA-6790907] Box C/D snoRNP methylates ribonucleotides in pre-rRNA yielding 2'-O-methylribonucleotides [Reaction:R-HSA-6790905] Box H/ACA snoRNP transforms uridine to pseudouridine in pre-rRNA
(hasEvent)	[Pathway:R-HSA-73863] RNA Polymerase I Transcription Termination