Reactome | RPE dimers isomerise RU5P to XY5P

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RPE dimers isomerise RU5P to XY5P Show undefined attributes

catalystActivity	[CatalystActivity:71302] D-ribulose-phosphate 3-epimerase activity of RPE:Fe2+ dimers [cytosol]
catalystActivityReference	[CatalystActivityReference:9643472] ribulose-phosphate 3-epimerase activity of RPE:Fe2+ dimers [cytosol] Biochemical genetics of the pentose phosphate cycle: human ribose 5-phosphate isomerase (RPI) and ribulose 5-phosphate 3-epimerase (RPE)
category	transition
compartment	[Compartment:70101] cytosol
crossReference	[DatabaseIdentifier:12667747] RHEA:13678 [DatabaseIdentifier:9934044] RHEA:13678
dbId	71303
displayName	RPE dimers isomerise RU5P to XY5P
edited	[InstanceEdit:8957344] Jassal, Bijay, 2017-01-25
eventOf	[Pathway:R-HSA-71336] Pentose phosphate pathway - Homo sapiens
followingEvent	[Reaction:R-HSA-71335] xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate - Homo sapiens [Reaction:R-HSA-71324] ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate - Homo sapiens
input	[SimpleEntity:R-ALL-29732] RU5P [cytosol]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:199804] Phosphoribosylpyrophosphate synthesis from glucose decreases during amino acid starvation of human lymphoblasts [LiteratureReference:467370] Biochemical genetics of the pentose phosphate cycle: human ribose 5-phosphate isomerase (RPI) and ribulose 5-phosphate 3-epimerase (RPE) [LiteratureReference:8957342] Conversion of D-ribulose 5-phosphate to D-xylulose 5-phosphate: new insights from structural and biochemical studies on human RPE
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	RPE dimers isomerise RU5P to XY5P D-ribulose 5-phosphate <=> xylulose 5-phosphate
orthologousEvent	[Reaction:R-PFA-71303] RPE dimers isomerise RU5P to XY5P - Plasmodium falciparum [Reaction:R-SCE-71303] RPE dimers isomerise RU5P to XY5P - Saccharomyces cerevisiae [Reaction:R-SPO-71303] RPE dimers isomerise RU5P to XY5P - Schizosaccharomyces pombe [Reaction:R-DDI-71303] RPE dimers isomerise RU5P to XY5P - Dictyostelium discoideum [Reaction:R-CEL-71303] RPE dimers isomerise RU5P to XY5P - Caenorhabditis elegans [Reaction:R-DME-71303] RPE dimers isomerise RU5P to XY5P - Drosophila melanogaster [Reaction:R-GGA-71303] RPE dimers isomerise RU5P to XY5P - Gallus gallus [Reaction:R-XTR-71303] RPE dimers isomerise RU5P to XY5P - Xenopus tropicalis [Reaction:R-DRE-71303] RPE dimers isomerise RU5P to XY5P - Danio rerio [Reaction:R-SSC-71303] RPE dimers isomerise RU5P to XY5P - Sus scrofa [Reaction:R-BTA-71303] RPE dimers isomerise RU5P to XY5P - Bos taurus [Reaction:R-CFA-71303] RPE dimers isomerise RU5P to XY5P - Canis familiaris [Reaction:R-RNO-71303] RPE dimers isomerise RU5P to XY5P - Rattus norvegicus [Reaction:R-MMU-71303] RPE dimers isomerise RU5P to XY5P - Mus musculus
output	[SimpleEntity:R-ALL-29790] XY5P [cytosol]
precedingEvent	[Reaction:R-HSA-71299] PGD decarboxylates 6-phospho-D-gluconate - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
revised	[InstanceEdit:8957344] Jassal, Bijay, 2017-01-25 [InstanceEdit:469644] D'Eustachio, P, 2010-01-24
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-71303
summation	[Summation:178640] Cytosolic ribulose-5-phosphate-3-epimerase (RPE), using Fe2+...
updateTrackers	[UpdateTracker:9791147] Update Tracker - [Reaction:71303] RPE dimers isomerise RU5P to XY5P - v32:[addLiteratureReference, modifyText] [UpdateTracker:9781588] Update Tracker - [Reaction:71303] RPE dimers isomerise RU5P to XY5P - v60:[addLiteratureReference, modifyText] [UpdateTracker:9792240] Update Tracker - [Reaction:71303] RPE dimers isomerise RU5P to XY5P - v22:[addLiteratureReference]

Referrals

(updatedInstance)	[UpdateTracker:9791147] Update Tracker - [Reaction:71303] RPE dimers isomerise RU5P to XY5P - v32:[addLiteratureReference, modifyText] [UpdateTracker:9781588] Update Tracker - [Reaction:71303] RPE dimers isomerise RU5P to XY5P - v60:[addLiteratureReference, modifyText] [UpdateTracker:9792240] Update Tracker - [Reaction:71303] RPE dimers isomerise RU5P to XY5P - v22:[addLiteratureReference]
(hasEvent)	[Pathway:R-HSA-71336] Pentose phosphate pathway
(precedingEvent)	[Reaction:R-HSA-71324] ribose 5-phosphate + xylulose 5-phosphate <=> sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate [Reaction:R-HSA-71335] xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate
(reverseReaction)	[Reaction:R-HSA-199803] RPE dimers isomerize XY5P to RU5P

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