xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate

catalystActivity
catalystActivityReference [CatalystActivityReference:9643773] transketolase activity of TKT dimer [cytosol] Aspartate 155 of human transketolase is essential for thiamine diphosphate-magnesium binding, and cofactor binding is required for dimer formation
category transition
compartment
crossReference
dbId 71335
displayName xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate
eventOf
input
isInDisease false
isInferred false
literatureReference
maxDepth 1
modified [InstanceEdit:10914110] Weiser, Joel, 2026-03-16
name
  • xylulose 5-phosphate + D-erythrose 4-phosphate <=> D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate
  • TKT dimer transfers two-carbon ketol group onto E4P
orthologousEvent
output
precedingEvent
releaseDate 2004-07-06
reverseReaction [Reaction:R-HSA-163751] D-glyceraldehyde 3-phosphate + D-fructose 6-phosphate <=> xylulose 5-phosphate + D-erythrose 4-phosphate
reviewStatus [ReviewStatus:9821382] five stars
revised
schemaClass Reaction
species
stId R-HSA-71335
summation
updateTrackers
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