Reactome | Mitotic Spindle Checkpoint

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Mitotic Spindle Checkpoint Show undefined attributes

authored	[InstanceEdit:143430] Yen, T, 2004-05-05 00:00:00
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:143430] Yen, T, 2004-05-05 00:00:00
dbId	69618
deleted	[Deleted:1591218] Deletion of instance: 141404 [Deleted:1591214] Deletion of instance: 141401 [Deleted:1591213] Deletion of instance: 141407 [Deleted:1591215] Deletion of instance: 141428
displayName	Mitotic Spindle Checkpoint
doi	10.3180/REACT_2137.1
eventOf	[Pathway:R-HSA-69620] Cell Cycle Checkpoints - Homo sapiens
followingEvent	[Pathway:R-HSA-68881] Mitotic Metaphase/Anaphase Transition - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:18633] mitotic spindle assembly checkpoint signaling
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-141424] Amplification of signal from the kinetochores - Homo sapiens [Pathway:R-HSA-141405] Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2017-06-22
literatureReference	[LiteratureReference:143454] The mitotic checkpoint: a signaling pathway that allows a single unattached kinetochore to inhibit mitotic exit [LiteratureReference:143445] The spindle checkpoint: structural insights into dynamic signalling
maxDepth	4
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Mitotic Spindle Checkpoint
orthologousEvent	[Pathway:R-SCE-69618] Mitotic Spindle Checkpoint - Saccharomyces cerevisiae [Pathway:R-SPO-69618] Mitotic Spindle Checkpoint - Schizosaccharomyces pombe [Pathway:R-DDI-69618] Mitotic Spindle Checkpoint - Dictyostelium discoideum [Pathway:R-CEL-69618] Mitotic Spindle Checkpoint - Caenorhabditis elegans [Pathway:R-DME-69618] Mitotic Spindle Checkpoint - Drosophila melanogaster [Pathway:R-GGA-69618] Mitotic Spindle Checkpoint - Gallus gallus [Pathway:R-XTR-69618] Mitotic Spindle Checkpoint - Xenopus tropicalis [Pathway:R-DRE-69618] Mitotic Spindle Checkpoint - Danio rerio [Pathway:R-SSC-69618] Mitotic Spindle Checkpoint - Sus scrofa [Pathway:R-BTA-69618] Mitotic Spindle Checkpoint - Bos taurus [Pathway:R-CFA-69618] Mitotic Spindle Checkpoint - Canis familiaris [Pathway:R-RNO-69618] Mitotic Spindle Checkpoint - Rattus norvegicus [Pathway:R-MMU-69618] Mitotic Spindle Checkpoint - Mus musculus
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-69618
summation	[Summation:141417] The mitotic checkpoint or spindle assembly checkpoint is an ...
updateTrackers	[UpdateTracker:9789500] Update Tracker - [Pathway:69618] Mitotic Spindle Checkpoint - v38:[modifyText, removeHasEvent, updateContainedPathway] [UpdateTracker:9788675] Update Tracker - [Pathway:69618] Mitotic Spindle Checkpoint - v41:[modifyText] [UpdateTracker:9780987] Update Tracker - [Pathway:69618] Mitotic Spindle Checkpoint - v61:[updateIndirectRLE]

Referrals

(updatedInstance)	[UpdateTracker:9789500] Update Tracker - [Pathway:69618] Mitotic Spindle Checkpoint - v38:[modifyText, removeHasEvent, updateContainedPathway] [UpdateTracker:9788675] Update Tracker - [Pathway:69618] Mitotic Spindle Checkpoint - v41:[modifyText] [UpdateTracker:9780987] Update Tracker - [Pathway:69618] Mitotic Spindle Checkpoint - v61:[updateIndirectRLE]
(replacementInstances)	[Deleted:1591218] Deletion of instance: 141404 [Deleted:1591214] Deletion of instance: 141401 [Deleted:1591213] Deletion of instance: 141407 [Deleted:1591215] Deletion of instance: 141428
(precedingEvent)	[Pathway:R-HSA-68881] Mitotic Metaphase/Anaphase Transition
(hasEvent)	[Pathway:R-HSA-69620] Cell Cycle Checkpoints

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