Reactome | Mitotic Spindle Checkpoint

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Mitotic Spindle Checkpoint Show undefined attributes

compartment	[Compartment:70101] cytosol
created	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
dbId	10911140
displayName	Mitotic Spindle Checkpoint
eventOf	[Pathway:R-DME-69620] Cell Cycle Checkpoints - Drosophila melanogaster
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[Pathway:R-DME-68881] Mitotic Metaphase/Anaphase Transition - Drosophila melanogaster
goBiologicalProcess	[GO_BiologicalProcess:18633] mitotic spindle assembly checkpoint signaling
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-DME-141405] Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components - Drosophila melanogaster
inferredFrom	[Pathway:R-HSA-69618] Mitotic Spindle Checkpoint - Homo sapiens
isInDisease	false
isInferred	true
maxDepth	4
name	Mitotic Spindle Checkpoint
releaseDate	2026-03-25
schemaClass	Pathway
species	[Species:56210] Drosophila melanogaster
stId	R-DME-69618
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-DME-69620] Cell Cycle Checkpoints
(precedingEvent)	[Pathway:R-DME-68881] Mitotic Metaphase/Anaphase Transition
(inferredTo)	[Pathway:R-HSA-69618] Mitotic Spindle Checkpoint

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