Reactome | Mitotic Metaphase/Anaphase Transition

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Mitotic Metaphase/Anaphase Transition Show undefined attributes

crossReference	[DatabaseIdentifier:12819537] BioModels Database:BIOMD0000000700 [DatabaseIdentifier:12819589] BioModels Database:BIOMD0000000954
dbId	68881
definition	The onset of anaphase in mitosis, triggered by the destruction of mitotic cyclins. definition_
displayName	Mitotic Metaphase/Anaphase Transition
eventOf	[Pathway:R-HSA-2555396] Mitotic Metaphase and Anaphase - Homo sapiens
followingEvent	[Pathway:R-HSA-68882] Mitotic Anaphase - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:18623] metaphase/anaphase transition of mitotic cell cycle
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-163010] Down Regulation of Emi1 through Phosphorylation of Emi1 - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2018-09-30
maxDepth	2
modified	[InstanceEdit:12819426] Weiser, Joel, 2026-02-23
name	Mitotic Metaphase/Anaphase Transition
orthologousEvent	[Pathway:R-BTA-68881] Mitotic Metaphase/Anaphase Transition - Bos taurus [Pathway:R-DME-68881] Mitotic Metaphase/Anaphase Transition - Drosophila melanogaster [Pathway:R-GGA-68881] Mitotic Metaphase/Anaphase Transition - Gallus gallus [Pathway:R-XTR-68881] Mitotic Metaphase/Anaphase Transition - Xenopus tropicalis [Pathway:R-DRE-68881] Mitotic Metaphase/Anaphase Transition - Danio rerio [Pathway:R-SSC-68881] Mitotic Metaphase/Anaphase Transition - Sus scrofa [Pathway:R-CFA-68881] Mitotic Metaphase/Anaphase Transition - Canis familiaris [Pathway:R-RNO-68881] Mitotic Metaphase/Anaphase Transition - Rattus norvegicus [Pathway:R-MMU-68881] Mitotic Metaphase/Anaphase Transition - Mus musculus
precedingEvent	[Pathway:R-HSA-69618] Mitotic Spindle Checkpoint - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-68881
summation	[Summation:212966] The metaphase to anaphase transition during mitosis is trigg...
updateTrackers	[UpdateTracker:9788207] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v43:[removeHasEvent] [UpdateTracker:9779203] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v66:[updateContainedRLE] [UpdateTracker:9791890] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v25:[updateContainedRLE] [UpdateTracker:9789013] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v39:[updateContainedRLE] [UpdateTracker:9791980] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v24:[addSummation]

Referrals

(updatedInstance)	[UpdateTracker:9788207] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v43:[removeHasEvent] [UpdateTracker:9779203] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v66:[updateContainedRLE] [UpdateTracker:9791890] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v25:[updateContainedRLE] [UpdateTracker:9789013] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v39:[updateContainedRLE] [UpdateTracker:9791980] Update Tracker - [Pathway:68881] Mitotic Metaphase/Anaphase Transition - v24:[addSummation]
(hasEvent)	[Pathway:R-HSA-2555396] Mitotic Metaphase and Anaphase
(precedingEvent)	[Pathway:R-HSA-68882] Mitotic Anaphase