Reactome | Mcm2-7 is phosphorylated by DDK

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Mcm2-7 is phosphorylated by DDK Show undefined attributes

catalystActivity	[CatalystActivity:68401] protein tyrosine kinase activity of DDK [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:68951] Davey, MJ, O'Donnell, M, 2003-06-05 08:03:13
dbId	68954
displayName	Mcm2-7 is phosphorylated by DDK
eventOf	[Pathway:R-HSA-68962] Activation of the pre-replicative complex - Homo sapiens
input	[SimpleEntity:R-ALL-29358] ATP [nucleoplasm] [Complex:R-HSA-68558] MCM2-7 [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:68955] Human Cdc7-related kinase complex. In vitro phosphorylation of MCM by concerted actions of Cdks and Cdc7 and that of a critical threonine residue of Cdc7 by Cdks.
maxDepth	1
modified	[InstanceEdit:11080360] Weiser, Joel, 2026-03-16
name	Mcm2-7 is phosphorylated by DDK
orthologousEvent	[Reaction:R-SCE-68954] Mcm2-7 is phosphorylated by DDK - Saccharomyces cerevisiae [Reaction:R-SPO-68954] Mcm2-7 is phosphorylated by DDK - Schizosaccharomyces pombe [Reaction:R-GGA-68954] Mcm2-7 is phosphorylated by DDK - Gallus gallus [Reaction:R-DRE-68954] Mcm2-7 is phosphorylated by DDK - Danio rerio [Reaction:R-SSC-68954] Mcm2-7 is phosphorylated by DDK - Sus scrofa [Reaction:R-BTA-68954] Mcm2-7 is phosphorylated by DDK - Bos taurus [Reaction:R-RNO-68954] Mcm2-7 is phosphorylated by DDK - Rattus norvegicus [Reaction:R-MMU-68954] Mcm2-7 is phosphorylated by DDK - Mus musculus
output	[SimpleEntity:R-ALL-113582] ADP [nucleoplasm] [Complex:R-HSA-68569] p-MCM2-7 [nucleoplasm]
precedingEvent	[Reaction:R-HSA-68918] CDK and DDK associate with the Mcm10:pre-replicative complex - Homo sapiens
releaseDate	2004-07-06
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-68954
summation	[Summation:178948] At the beginning of this reaction, 1 molecule of 'Mcm2-7 com...

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(hasEvent)

[Pathway:R-HSA-68962] Activation of the pre-replicative complex