Reactome | CDK4 [cytosol]

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-68334] CDK4:CCND3 [cytosol] - Homo sapiens [Complex:R-HSA-75814] phospho(T286)-Cyclin D1:Cdk4 [cytosol] - Homo sapiens
consumedByEvent	[FailedReaction:R-HSA-9630792] p16INK4A mutants do not bind CDK4 - Homo sapiens
dbId	68330
displayName	CDK4 [cytosol]
endCoordinate	303
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-68330] CDK4 [cytosol] - Mus musculus [EntityWithAccessionedSequence:R-RNO-68330] CDK4 [cytosol] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-68330] CDK4 [cytosol] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-68330] CDK4 [cytosol] - Bos taurus [EntityWithAccessionedSequence:R-SSC-68330] CDK4 [cytosol] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-68330] CDK4 [cytosol] - Danio rerio [EntityWithAccessionedSequence:R-XTR-68330] CDK4 [cytosol] - Xenopus tropicalis [EntityWithAccessionedSequence:R-DME-68330] CDK4 [cytosol] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-68330] CDK4 [cytosol] - Caenorhabditis elegans [EntityWithAccessionedSequence:R-DDI-68330] CDK4 [cytosol] - Dictyostelium discoideum [EntityWithAccessionedSequence:R-SPO-68330] CDK4 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SPO-68330-2] CDK4 [cytosol] - Schizosaccharomyces pombe [DefinedSet:R-SPO-68330-3] Homologues of CDK4 [cytosol] - Schizosaccharomyces pombe [EntityWithAccessionedSequence:R-SCE-68330] CDK4 [cytosol] - Saccharomyces cerevisiae [EntityWithAccessionedSequence:R-SCE-68330-2] CDK4 [cytosol] - Saccharomyces cerevisiae [DefinedSet:R-SCE-68330-3] Homologues of CDK4 [cytosol] - Saccharomyces cerevisiae
maxDepth	1
memberOf	[DefinedSet:R-HSA-69209] CDK4,CDK6 [cytosol] - Homo sapiens
modified	[InstanceEdit:4084552] Orlic-Milacic, M, 2013-07-29
name	CDK4 Cdk4 Cell division protein kinase 4 (EC 2.7.1.- ) (Cyclin-dependent kinase 4) (PSK-J3) (CDK4) Cell division protein kinase 4 Cyclin-dependent kinase 4 PSK-J3
referenceEntity	[ReferenceGeneProduct:uniprot:P11802] UniProt:P11802 CDK4
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-68330
startCoordinate	2
updateTrackers	[UpdateTracker:9883490] Update Tracker - [EntityWithAccessionedSequence:68330] CDK4 [cytosol] - v45:[addName] [UpdateTracker:9888389] Update Tracker - [EntityWithAccessionedSequence:68330] CDK4 [cytosol] - v46:[removeName] [UpdateTracker:9878224] Update Tracker - [EntityWithAccessionedSequence:68330] CDK4 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate]

(updatedInstance)	[UpdateTracker:9883490] Update Tracker - [EntityWithAccessionedSequence:68330] CDK4 [cytosol] - v45:[addName] [UpdateTracker:9888389] Update Tracker - [EntityWithAccessionedSequence:68330] CDK4 [cytosol] - v46:[removeName] [UpdateTracker:9878224] Update Tracker - [EntityWithAccessionedSequence:68330] CDK4 [cytosol] - v44:[modifyEndCoordinate, modifyStartCoordinate]
(input)	[FailedReaction:R-HSA-9630792] p16INK4A mutants do not bind CDK4
(activeUnit)	[CatalystActivity:9929492] cyclin-dependent protein serine/threonine kinase activity of CDK4:CCND1 [cytosol]
(hasComponent)	[Complex:R-HSA-75814] phospho(T286)-Cyclin D1:Cdk4 [cytosol] [Complex:R-HSA-68334] CDK4:CCND3 [cytosol] [Complex:R-HSA-68331] CDK4:CCND1 [cytosol] [Complex:R-HSA-68341] CDK4:CCND2 [cytosol]
(hasMember)	[DefinedSet:R-HSA-69209] CDK4,CDK6 [cytosol]

CDK4 [cytosol] Show undefined attributes

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