Reactome | Envoplakin binds periplakin

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Envoplakin binds periplakin Show undefined attributes

authored	[InstanceEdit:8863769] Jupe, Steve, 2016-03-10
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6810835] Jupe, Steve, 2015-11-19
dbId	6810843
displayName	Envoplakin binds periplakin
edited	[InstanceEdit:8934545] Jupe, Steve, 2016-08-10
eventOf	[Pathway:R-HSA-6809371] Formation of the cornified envelope - Homo sapiens
followingEvent	[Reaction:R-HSA-6814187] EVL:PPL heterodimer binds the inner surface of the plasma membrane - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6810853] EVPL [cytosol] [EntityWithAccessionedSequence:R-HSA-6810850] PPL [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6810932] Co-assembly of envoplakin and periplakin into oligomers and Ca(2+)-dependent vesicle binding: implications for cornified cell envelope formation in stratified squamous epithelia
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	Envoplakin binds periplakin
orthologousEvent	[Reaction:R-GGA-6810843] Envoplakin binds periplakin - Gallus gallus [Reaction:R-XTR-6810843] Envoplakin binds periplakin - Xenopus tropicalis [Reaction:R-DRE-6810843] Envoplakin binds periplakin - Danio rerio [Reaction:R-SSC-6810843] Envoplakin binds periplakin - Sus scrofa [Reaction:R-BTA-6810843] Envoplakin binds periplakin - Bos taurus [Reaction:R-CFA-6810843] Envoplakin binds periplakin - Canis familiaris [Reaction:R-RNO-6810843] Envoplakin binds periplakin - Rattus norvegicus [Reaction:R-MMU-6810843] Envoplakin binds periplakin - Mus musculus
output	[Complex:R-HSA-6814178] EVPL:PPL [cytosol]
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8934809] Blumenberg, Miroslav, 2016-08-12
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6810843
summation	[Summation:6810926] Envoplakin (EVPL) is insoluble under physiological condition...

Referrals

(hasEvent)	[Pathway:R-HSA-6809371] Formation of the cornified envelope
(precedingEvent)	[Reaction:R-HSA-6814187] EVL:PPL heterodimer binds the inner surface of the plasma membrane