Reactome | General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene

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General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene Show undefined attributes

authored	[InstanceEdit:6810224] May, Bruce, 2015-11-08
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6810237] May, Bruce, 2015-11-16
dbId	6810234
displayName	General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene
edited	[InstanceEdit:6810224] May, Bruce, 2015-11-08
eventOf	[Pathway:R-HSA-6807505] RNA polymerase II transcribes snRNA genes - Homo sapiens
followingEvent	[Reaction:R-HSA-6810238] RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-69218] CDK7 [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-65888] GTF2B [nucleoplasm] [Complex:R-HSA-112431] P-TEFb complex [nucleoplasm] [Complex:R-HSA-6810222] SNAPc:POU2F1,2:SP1:ZNF143:snRNA gene [nucleoplasm] [Complex:R-HSA-6810230] snTAFc [nucleoplasm] [EntityWithAccessionedSequence:R-HSA-83718] TBP [nucleoplasm] [Complex:R-HSA-109629] TFIIA [nucleoplasm] [Complex:R-HSA-109633] TFIIE [nucleoplasm] [Complex:R-HSA-109631] TFIIF [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6814503] The general transcription factors IIA, IIB, IIF, and IIE are required for RNA polymerase II transcription from the human U1 small nuclear RNA promoter [LiteratureReference:6810211] A novel TBP-TAF complex on RNA polymerase II-transcribed snRNA genes [LiteratureReference:6814462] Common and unique transcription factor requirements of human U1 and U6 snRNA genes [LiteratureReference:83859] Targeting TBP to a non-TATA box cis-regulatory element: a TBP-containing complex activates transcription from snRNA promoters through the PSE [LiteratureReference:6814926] P-TEFb is not an essential elongation factor for the intronless human U2 snRNA and histone H2b genes [LiteratureReference:6810201] TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II
maxDepth	1
modified	[InstanceEdit:10559787] Weiser, Joel, 2026-03-16
name	General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene
orthologousEvent	[Reaction:R-DRE-6810234] General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene - Danio rerio [Reaction:R-BTA-6810234] General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene - Bos taurus [Reaction:R-RNO-6810234] General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene - Rattus norvegicus [Reaction:R-MMU-6810234] General transcription factors bind SNAPc:POU2F1:ZNF143:snRNA gene - Mus musculus
output	[Complex:R-HSA-6810225] Initiation factors:CDK7:snRNA gene [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6810239] SNAPc binds PSE of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12) - Homo sapiens
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8858395] Hernandez, Nouria, 2016-02-19
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6810234
summation	[Summation:6814927] The promoter of an snRNA gene binds the basal transcription ...

Referrals

(hasEvent)	[Pathway:R-HSA-6807505] RNA polymerase II transcribes snRNA genes
(precedingEvent)	[Reaction:R-HSA-6810238] RNA polymerase II binds initiation factors at promoter of snRNA gene (U1, U2, U4, U4atac, U5, U11, U12)