Reactome | TP53 stimulates RGCC expression

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TP53 stimulates RGCC expression Show undefined attributes

authored	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
category	omitted
compartment	[Compartment:70101] cytosol [Compartment:7660] nucleoplasm
created	[InstanceEdit:6803910] Orlic-Milacic, Marija, 2015-10-07
dbId	6803917
displayName	TP53 stimulates RGCC expression
edited	[InstanceEdit:6804719] Orlic-Milacic, Marija, 2015-10-14
eventOf	[Pathway:R-HSA-6804115] TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain - Homo sapiens
input	[EntityWithAccessionedSequence:R-HSA-6803905] RGCC Gene [nucleoplasm]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6803912] RGC32, a novel p53-inducible gene, is located on centrosomes during mitosis and results in G2/M arrest [LiteratureReference:6803922] Overexpression of RGC-32 in colon cancer and other tumors
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	TP53 stimulates RGCC expression
output	[EntityWithAccessionedSequence:R-HSA-6803902] RGCC [cytosol]
precedingEvent	[Reaction:R-HSA-6803914] TP53 binds the RGCC gene - Homo sapiens
regulatedBy	[PositiveGeneExpressionRegulation:R-HSA-6803923] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:RGCC Gene [nucleoplasm]'
regulationReference	[RegulationReference:9641967] Positive gene expression regulation by 'p-S15,S20-TP53 Tetramer:RGCC Gene [nucleoplasm]' RGC32, a novel p53-inducible gene, is located on centrosomes during mitosis and results in G2/M arrest
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8855677] Zaccara, Sara, 2016-02-04 [InstanceEdit:8855680] Inga, Alberto, 2016-02-04
schemaClass	BlackBoxEvent
species	[Species:48887] Homo sapiens
stId	R-HSA-6803917
summation	[Summation:6803915] Binding of TP53 (p53) to the p53 response element in the sec...

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(hasEvent)

[Pathway:R-HSA-6804115] TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain

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