Reactome | RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane]

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RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:6802843] protein serine/threonine kinase activity of RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-6802919] RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks - Homo sapiens
created	[InstanceEdit:6802644] Rothfels, Karen, 2015-10-02
dbId	6802645
displayName	RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
hasComponent	[DefinedSet:R-HSA-5672716] MAP2K homo/heterodimers [cytosol] [DefinedSet:R-HSA-169291] MAPKs [cytosol] [CandidateSet:R-HSA-5672717] RAF/MAPK scaffolds [cytosol] [Complex:R-HSA-6802642] RAS:GTP:moderate kinase activity BRAF mutants:p-RAF:YWHAB [plasma membrane]
inDisease	false
includedLocation	[Compartment:70101] cytosol
isChimeric	false
maxDepth	11
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins
producedByEvent	[Reaction:R-HSA-6802914] RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6802645
updateTrackers	[UpdateTracker:9899947] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v67:[updateContainedComponent] [UpdateTracker:9928653] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v91:[updateContainedComponent] [UpdateTracker:9898608] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v64:[updateContainedComponent] [UpdateTracker:9919910] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v90:[updateContainedComponent] [UpdateTracker:9896802] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v60:[updateContainedComponent] [UpdateTracker:9900890] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v70:[updateContainedComponent] [UpdateTracker:9898008] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v63:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9899947] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v67:[updateContainedComponent] [UpdateTracker:9928653] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v91:[updateContainedComponent] [UpdateTracker:9898608] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v64:[updateContainedComponent] [UpdateTracker:9919910] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v90:[updateContainedComponent] [UpdateTracker:9896802] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v60:[updateContainedComponent] [UpdateTracker:9900890] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v70:[updateContainedComponent] [UpdateTracker:9898008] Update Tracker - [Complex:6802645] RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane] - v63:[updateContainedComponent]
(output)	[Reaction:R-HSA-6802914] RAS:GTP:moderate kinase activity p-RAF complexes bind MAP2Ks and MAPKs
(input)	[Reaction:R-HSA-6802919] RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks
(diseaseEntity)	[EntityFunctionalStatus:6802877] gain_of_function of RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane]
(physicalEntity)	[CatalystActivity:6802843] protein serine/threonine kinase activity of RAS:GTP:moderate kinase activity p-RAF:MAP2Ks:MAPKs:scaffold proteins [plasma membrane]

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