Reactome | MPRIP(2-1015)-p-RAF1(279-648) fusion [cytosol]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:70101] cytosol
componentOf	[Complex:R-HSA-6802704] p-MPRIP-RAF1 fusion dimer [cytosol] - Homo sapiens [Complex:R-HSA-6802704] p-MPRIP-RAF1 fusion dimer [cytosol] - Homo sapiens
created	[InstanceEdit:6802539] Rothfels, Karen, 2015-10-02
crossReference	[DatabaseIdentifier:12021100] Mondo:0005012
dbId	6802540
disease	[Disease:1500689] cancer [Disease:6802273] skin melanoma
displayName	MPRIP(2-1015)-p-RAF1(279-648) fusion [cytosol]
endCoordinate	1015
hasModifiedResidue	[FragmentInsertionModification:6802407] Insertion of residues 279 to 648 at 1016 from UniProt:P04049 RAF1 [ModifiedResidue:109785] O-phospho-L-serine at 621 [ModifiedResidue:444234] O-phospho-L-serine at 338 [ModifiedResidue:109791] O4'-phospho-L-tyrosine at 341 [ModifiedResidue:5672662] O-phospho-L-threonine at 491 [ModifiedResidue:5672663] O-phospho-L-serine at 494
inDisease	true
literatureReference	[LiteratureReference:6800639] The landscape of kinase fusions in cancer
maxDepth	1
modified	[InstanceEdit:9753817] Rothfels, Karen, 2021-09-13
name	MPRIP(2-1015)-p-RAF1(279-648) fusion
referenceEntity	[ReferenceGeneProduct:uniprot:Q6WCQ1] UniProt:Q6WCQ1 MPRIP
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6802540
startCoordinate	2
updateTrackers	[UpdateTracker:9902949] Update Tracker - [EntityWithAccessionedSequence:6802540] MPRIP(2-1015)-p-RAF1(279-648) fusion [cytosol] - v79:[modifyName]

(updatedInstance)	[UpdateTracker:9902949] Update Tracker - [EntityWithAccessionedSequence:6802540] MPRIP(2-1015)-p-RAF1(279-648) fusion [cytosol] - v79:[modifyName]
(hasComponent)	[Complex:R-HSA-6802704] p-MPRIP-RAF1 fusion dimer [cytosol]

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