Reactome | KRAS G12C [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

compartment	[Compartment:876] plasma membrane
created	[InstanceEdit:6802330] Rothfels, Karen, 2015-10-02
crossReference	[DatabaseIdentifier:12020779] Mondo:0009831 [DatabaseIdentifier:6802329] COSMIC:COSV55497469
dbId	6802331
disease	[Disease:1500699] lung cancer [Disease:4791250] colorectal cancer [Disease:2328198] pancreatic cancer
displayName	KRAS G12C [plasma membrane]
endCoordinate	186
hasModifiedResidue	[ReplacedResidue:6802328] glycine 12 replaced with L-cysteine
inDisease	true
maxDepth	1
memberOf	[CandidateSet:R-HSA-6802608] RAS GTPase mutants [plasma membrane] - Homo sapiens [CandidateSet:R-HSA-9651281] RAS GAP mutants [plasma membrane] - Homo sapiens
modified	[InstanceEdit:9646281] Rothfels, Karen, 2019-05-21
name	KRAS G12C
referenceEntity	[ReferenceGeneProduct:uniprot:P01116] UniProt:P01116 KRAS
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-6802331
startCoordinate	1
updateTrackers	[UpdateTracker:9900725] Update Tracker - [EntityWithAccessionedSequence:6802331] KRAS G12C [plasma membrane] - v70:[modifyName]

(updatedInstance)	[UpdateTracker:9900725] Update Tracker - [EntityWithAccessionedSequence:6802331] KRAS G12C [plasma membrane] - v70:[modifyName]
(hasMember)	[CandidateSet:R-HSA-6802608] RAS GTPase mutants [plasma membrane] [CandidateSet:R-HSA-9651281] RAS GAP mutants [plasma membrane]

Cite Us!