Reactome | N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer

Schema > Reaction > Entries

N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer Show undefined attributes

authored	[InstanceEdit:6800142] Jassal, Bijay, 2015-09-28
catalystActivity	[CatalystActivity:6800151] protein-glutamine N-methyltransferase activity of N6AMT1:TRMT112 [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6800142] Jassal, Bijay, 2015-09-28
dbId	6800138
displayName	N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer
edited	[InstanceEdit:6800142] Jassal, Bijay, 2015-09-28
eventOf	[Pathway:R-HSA-72764] Eukaryotic Translation Termination - Homo sapiens
followingEvent	[Reaction:R-HSA-141691] GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex - Homo sapiens
input	2 × [SimpleEntity:R-ALL-71284] AdoMet [cytosol] [Complex:R-HSA-6800132] ETF1 dimer:eRF3:GTP [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6800145] HemK2 protein, encoded on human chromosome 21, methylates translation termination factor eRF1
maxDepth	1
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer
orthologousEvent	[Reaction:R-PFA-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Plasmodium falciparum [Reaction:R-SCE-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Saccharomyces cerevisiae [Reaction:R-SPO-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Schizosaccharomyces pombe [Reaction:R-DDI-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Dictyostelium discoideum [Reaction:R-CEL-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Caenorhabditis elegans [Reaction:R-DME-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Drosophila melanogaster [Reaction:R-XTR-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Xenopus tropicalis [Reaction:R-DRE-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Danio rerio [Reaction:R-SSC-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Sus scrofa [Reaction:R-BTA-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Bos taurus [Reaction:R-CFA-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Canis familiaris [Reaction:R-MMU-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Mus musculus
output	2 × [SimpleEntity:R-ALL-71285] AdoHcy [cytosol] [Complex:R-HSA-6800154] Me-Q185-ETF1 dimer:eRF3:GTP [cytosol]
releaseDate	2016-03-23
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8851787] D'Eustachio, Peter, 2016-01-11
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6800138
summation	[Summation:6800148] Class 1 release factors such as eukaryotic peptide chain rel...

Referrals

(hasEvent)	[Pathway:R-HSA-72764] Eukaryotic Translation Termination
(precedingEvent)	[Reaction:R-HSA-141691] GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex