Reactome | GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex

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GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex Show undefined attributes

authored	[InstanceEdit:158455] Gillespie, ME, 2005-01-26 20:24:54
category	binding
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:157572] Bedwell, D, 2005-01-03 15:16:42
dbId	141691
displayName	GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex
eventOf	[Pathway:R-HSA-72764] Eukaryotic Translation Termination - Homo sapiens
figure	[Figure:141692] /figures/transterm_eRF1andeRF3Bind.jpg
followingEvent	[Reaction:R-HSA-141673] GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:18536] translational termination
inferredFrom	[Reaction:R-SCE-141667] GTP bound eRF3:eRF1 complex binds the peptidyl-tRNA:mRNA:Ribosome complex - Saccharomyces cerevisiae
input	[Complex:R-HSA-141952] 80S Ribosome:mRNA:peptidyl-tRNA with elongating peptide [cytosol] [Complex:R-HSA-6800154] Me-Q185-ETF1 dimer:eRF3:GTP [cytosol]
isInDisease	false
isInferred	true
literatureReference	[LiteratureReference:143391] Molecular cloning of a novel member of the eukaryotic polypeptide chain-releasing factors (eRF). Its identification as eRF3 interacting with eRF1. [LiteratureReference:143367] A highly conserved eukaryotic protein family possessing properties of polypeptide chain release factor
maxDepth	1
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex
output	[Complex:R-HSA-143397] Me-Q185-ETF1 dimer:eRF3:GTP:80S Ribosome:mRNA:peptidyl-tRNA [cytosol]
precedingEvent	[Reaction:R-HSA-156915] Translocation of ribosome by 3 bases in the 3' direction - Homo sapiens [Reaction:R-HSA-6800138] N6AMT1:TRMT112 transfers CH3 group from AdoMet to ETF1 dimer - Homo sapiens
releaseDate	2004-10-27
reviewStatus	[ReviewStatus:9821382] five stars
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-141691
summation	[Summation:157356] Please note that this reaction was inferred from experiments...
updateTrackers	[UpdateTracker:9783456] Update Tracker - [Reaction:141691] GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex - v56:[add_removeInput]

Referrals

(updatedInstance)	[UpdateTracker:9783456] Update Tracker - [Reaction:141691] GTP bound eRF3:eRF1 complex binds the peptidyl tRNA:mRNA:80S Ribosome complex - v56:[add_removeInput]
(hasEvent)	[Pathway:R-HSA-72764] Eukaryotic Translation Termination
(precedingEvent)	[Reaction:R-HSA-141673] GTP Hydrolysis by eRF3 bound to the eRF1:mRNA:polypeptide:80S Ribosome complex
(inferredTo)	[Reaction:R-SCE-141667] GTP bound eRF3:eRF1 complex binds the peptidyl-tRNA:mRNA:Ribosome complex

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