Reactome | PGLYRP2 binds bacterial peptidoglycan

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PGLYRP2 binds bacterial peptidoglycan Show undefined attributes

authored	[InstanceEdit:6803156] Shamovsky, Veronica, 2015-10-05
category	binding
compartment	[Compartment:984] extracellular region [Compartment:25409] peptidoglycan-based cell wall
created	[InstanceEdit:6799986] Shamovsky, Veronica, 2015-09-26
dbId	6799981
displayName	PGLYRP2 binds bacterial peptidoglycan
edited	[InstanceEdit:8935852] Shamovsky, Veronica, 2016-08-15
entityOnOtherCell	[Polymer:R-ALL-6788957] GlcNAc(1-->4)MurNAc:L-Ala-gamma-D-Glu-L-Lys-(D-Ala)2 [peptidoglycan-based cell wall]
eventOf	[Pathway:R-HSA-6803157] Antimicrobial peptides - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-6799977] PGLYRP2 hydrolyzes bacterial peptidoglycan - Homo sapiens
input	[SimpleEntity:R-ALL-6789198] GlcNac-(1-->4)MurNAc-L-Ala-gamma-D-Glu-L-Lys-(D-Ala)2 [peptidoglycan-based cell wall] [Complex:R-HSA-8933468] PGLYRP2 dimer [extracellular region]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6788956] Human peptidoglycan recognition protein-L is an N-acetylmuramoyl-L-alanine amidase [LiteratureReference:6789060] Identification of serum N-acetylmuramoyl-l-alanine amidase as liver peptidoglycan recognition protein 2 [LiteratureReference:6789166] Peptidoglycan recognition proteins are a new class of human bactericidal proteins
maxDepth	1
modified	[InstanceEdit:10829237] Weiser, Joel, 2026-03-16
name	PGLYRP2 binds bacterial peptidoglycan
orthologousEvent	[Reaction:R-MMU-6799981] PGLYRP2 binds bacterial peptidoglycan - Mus musculus [Reaction:R-DME-6799981] PGLYRP2 binds bacterial peptidoglycan - Drosophila melanogaster [Reaction:R-GGA-6799981] PGLYRP2 binds bacterial peptidoglycan - Gallus gallus [Reaction:R-XTR-6799981] PGLYRP2 binds bacterial peptidoglycan - Xenopus tropicalis [Reaction:R-DRE-6799981] PGLYRP2 binds bacterial peptidoglycan - Danio rerio [Reaction:R-SSC-6799981] PGLYRP2 binds bacterial peptidoglycan - Sus scrofa [Reaction:R-BTA-6799981] PGLYRP2 binds bacterial peptidoglycan - Bos taurus [Reaction:R-CFA-6799981] PGLYRP2 binds bacterial peptidoglycan - Canis familiaris [Reaction:R-RNO-6799981] PGLYRP2 binds bacterial peptidoglycan - Rattus norvegicus
output	[Complex:R-HSA-6799988] PGLYRP2:peptidoglycan [extracellular region]
releaseDate	2016-09-19
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:8933043] Dziarski, Roman, 2016-08-02 [InstanceEdit:8933035] Hains, David S, 2016-08-02 [InstanceEdit:8867536] Jupe, Steve, 2016-04-15
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6799981
summation	[Summation:6799976] Peptidoglycan recognition proteins (PGRPs or PGLYRPs) are in...

Referrals

(hasEvent)	[Pathway:R-HSA-6803157] Antimicrobial peptides
(precedingEvent)	[BlackBoxEvent:R-HSA-6799977] PGLYRP2 hydrolyzes bacterial peptidoglycan