Reactome | PGLYRP2 binds bacterial peptidoglycan

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PGLYRP2 binds bacterial peptidoglycan Show undefined attributes

category	binding
compartment	[Compartment:984] extracellular region [Compartment:25409] peptidoglycan-based cell wall
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10193323
displayName	PGLYRP2 binds bacterial peptidoglycan
eventOf	[Pathway:R-RNO-6803157] Antimicrobial peptides - Rattus norvegicus
evidenceType	[EvidenceType:9984902] inferred by electronic annotation
followingEvent	[BlackBoxEvent:R-RNO-6799977] PGLYRP2 hydrolyzes bacterial peptidoglycan - Rattus norvegicus
inferredFrom	[Reaction:R-HSA-6799981] PGLYRP2 binds bacterial peptidoglycan - Homo sapiens
input	[SimpleEntity:R-ALL-6789198] GlcNac-(1-->4)MurNAc-L-Ala-gamma-D-Glu-L-Lys-(D-Ala)2 [peptidoglycan-based cell wall] [Complex:R-RNO-8933468] PGLYRP2 dimer [extracellular region]
isInDisease	false
isInferred	true
maxDepth	1
name	PGLYRP2 binds bacterial peptidoglycan
output	[Complex:R-RNO-6799988] PGLYRP2:peptidoglycan [extracellular region]
releaseDate	2026-03-25
schemaClass	Reaction
species	[Species:48895] Rattus norvegicus
stId	R-RNO-6799981
summation	[Summation:9984901] This event has been computationally inferred from an event that has been demonstrated in another species. The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation. More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Referrals

(hasEvent)	[Pathway:R-RNO-6803157] Antimicrobial peptides
(precedingEvent)	[BlackBoxEvent:R-RNO-6799977] PGLYRP2 hydrolyzes bacterial peptidoglycan
(inferredTo)	[Reaction:R-HSA-6799981] PGLYRP2 binds bacterial peptidoglycan

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