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Entries
Major pathway of rRNA processing in the nucleolus and cytosol
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authored
[InstanceEdit:6791012] May, Bruce, 2015-08-16
created
[InstanceEdit:6791220] May, Bruce, 2015-08-19
dbId
6791226
displayName
Major pathway of rRNA processing in the nucleolus and cytosol
doi
10.3180/r-hsa-6791226.1
edited
[InstanceEdit:6791012] May, Bruce, 2015-08-16
eventOf
[Pathway:R-HSA-8868773] rRNA processing in the nucleus and cytosol - Homo sapiens
goBiologicalProcess
[GO_BiologicalProcess:17838] rRNA processing
hasDiagram
true
hasEHLD
false
hasEvent
[BlackBoxEvent:R-HSA-6791227] 47S pre-rRNA is nucleolytically processed at A' (01,A1), site A0, and site 02 (site 6) to yield 45S pre-rRNA - Homo sapiens
[BlackBoxEvent:R-HSA-6791228] 45S pre-rRNA is nucleolytically processed at site 2 (site 2b) to yield 30S pre-rRNA and 32S pre-rRNA - Homo sapiens
[BlackBoxEvent:R-HSA-6791221] 30S pre-rRNA is nucleolytically processed at site 1 to yield 21S pre-rRNA - Homo sapiens
[BlackBoxEvent:R-HSA-6791222] 21S pre-rRNA is nucleolytically processed at site E (site2a) to yield 18SE pre-rRNA - Homo sapiens
[BlackBoxEvent:R-HSA-6791223] 18SE pre-rRNA in pre-40S particles is nucleolytically processed during translocation from the nucleus to the cytosol - Homo sapiens
[BlackBoxEvent:R-HSA-6791219] 32S pre-rRNA is nucleolytically processed at site 4 (4a) to yield 12S pre-rRNA and 28S rRNA - Homo sapiens
[BlackBoxEvent:R-HSA-6791218] 12S pre-rRNA is nucleolytically processed to yield 5.8S rRNA - Homo sapiens
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:6790800] An overview of pre-ribosomal RNA processing in eukaryotes
[LiteratureReference:6791151] Mapping the cleavage sites on mammalian pre-rRNAs: where do we stand?
[LiteratureReference:6791155] The complexity of human ribosome biogenesis revealed by systematic nucleolar screening of Pre-rRNA processing factors
[LiteratureReference:6792643] The nucleolus: structure/function relationship in RNA metabolism
[LiteratureReference:6790796] The small subunit processome in ribosome biogenesis?progress and prospects
[LiteratureReference:6798730] Duration of the first steps of the human rRNA processing
[LiteratureReference:6807322] Non-isotopic mapping of ribosomal RNA synthesis and processing in the nucleolus
[LiteratureReference:6790852] A large nucleolar U3 ribonucleoprotein required for 18S ribosomal RNA biogenesis
[LiteratureReference:8855026] 90S pre-ribosomes include the 35S pre-rRNA, the U3 snoRNP, and 40S subunit processing factors but predominantly lack 60S synthesis factors
[LiteratureReference:8855029] A protein interaction map of the LSU processome
modified
[InstanceEdit:10931649] Wright, Adam, 2024-03-08
name
Major pathway of rRNA processing in the nucleolus and cytosol
orthologousEvent
[Pathway:R-PFA-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Plasmodium falciparum
[Pathway:R-SCE-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Saccharomyces cerevisiae
[Pathway:R-SPO-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Schizosaccharomyces pombe
[Pathway:R-DDI-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Dictyostelium discoideum
[Pathway:R-CEL-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Caenorhabditis elegans
[Pathway:R-DME-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Drosophila melanogaster
[Pathway:R-GGA-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Gallus gallus
[Pathway:R-XTR-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Xenopus tropicalis
[Pathway:R-SSC-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Sus scrofa
[Pathway:R-BTA-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Bos taurus
[Pathway:R-CFA-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Canis familiaris
[Pathway:R-RNO-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Rattus norvegicus
[Pathway:R-MMU-6791226] Major pathway of rRNA processing in the nucleolus and cytosol - Mus musculus
releaseDate
2016-03-23
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:8855036] Vincent, Nicholas G, 2016-01-30
schemaClass
Pathway
species
[Species:48887] Homo sapiens
stId
R-HSA-6791226
summation
[Summation:6791224] In humans, a 47S precursor rRNA (pre-rRNA) is transcribed by...
Referrals
(hasEvent)
[Pathway:R-HSA-8868773] rRNA processing in the nucleus and cytosol
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