Reactome | GDP-fucose biosynthesis

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GDP-fucose biosynthesis Show undefined attributes

authored	[InstanceEdit:6787603] Jassal, Bijay, 2015-07-15
created	[InstanceEdit:6787603] Jassal, Bijay, 2015-07-15
dbId	6787639
displayName	GDP-fucose biosynthesis
edited	[InstanceEdit:6787603] Jassal, Bijay, 2015-07-15
eventOf	[Pathway:R-HSA-446219] Synthesis of substrates in N-glycan biosythesis - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:11273] GDP-L-fucose biosynthetic process
hasDiagram	false
hasEHLD	false
hasEvent	[Reaction:R-HSA-6787632] GMDS dehydrates GDP-Man to GDP-DHDMan - Homo sapiens [Reaction:R-HSA-6787623] GFUS dimer epimerises GDP-DHDMan to GDP-KDGal - Homo sapiens [Reaction:R-HSA-6787642] GFUS dimer reduces GDP-KDGal to GDP-Fuc - Homo sapiens [Reaction:R-HSA-6787677] FUOM isomerises alpha-Fuc to beta-Fuc - Homo sapiens [Reaction:R-HSA-6787540] FCSK phosphorylates beta-Fuc to Fuc1P - Homo sapiens [Reaction:R-HSA-6787533] FPGT transfers guanylyl group from GTP to Fuc1P to form GDP-Fuc - Homo sapiens [Reaction:R-HSA-742345] SLC35C1 transports GDP-Fuc from cytosol to Golgi lumen - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-09-13
literatureReference	[LiteratureReference:6787663] Fucose: biosynthesis and biological function in mammals
maxDepth	2
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	GDP-fucose biosynthesis
orthologousEvent	[Pathway:R-PFA-6787639] GDP-fucose biosynthesis - Plasmodium falciparum [Pathway:R-SPO-6787639] GDP-fucose biosynthesis - Schizosaccharomyces pombe [Pathway:R-DDI-6787639] GDP-fucose biosynthesis - Dictyostelium discoideum [Pathway:R-CEL-6787639] GDP-fucose biosynthesis - Caenorhabditis elegans [Pathway:R-DME-6787639] GDP-fucose biosynthesis - Drosophila melanogaster [Pathway:R-GGA-6787639] GDP-fucose biosynthesis - Gallus gallus [Pathway:R-XTR-6787639] GDP-fucose biosynthesis - Xenopus tropicalis [Pathway:R-DRE-6787639] GDP-fucose biosynthesis - Danio rerio [Pathway:R-SSC-6787639] GDP-fucose biosynthesis - Sus scrofa [Pathway:R-BTA-6787639] GDP-fucose biosynthesis - Bos taurus [Pathway:R-CFA-6787639] GDP-fucose biosynthesis - Canis familiaris [Pathway:R-RNO-6787639] GDP-fucose biosynthesis - Rattus norvegicus [Pathway:R-MMU-6787639] GDP-fucose biosynthesis - Mus musculus
releaseDate	2015-12-15
releaseStatus	UPDATED
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6797578] D'Eustachio, Peter, 2015-09-14
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-6787639
summation	[Summation:6787641] Fucose-containing glycans play important roles in immunity a...
updateTrackers	[UpdateTracker:9842276] Update Tracker - [Pathway:6787639] GDP-fucose biosynthesis - v86:[updateContainedRLE]

Referrals

(updatedInstance)	[UpdateTracker:9842276] Update Tracker - [Pathway:6787639] GDP-fucose biosynthesis - v86:[updateContainedRLE]
(hasEvent)	[Pathway:R-HSA-446219] Synthesis of substrates in N-glycan biosythesis