Reactome | Synthesis of substrates in N-glycan biosythesis

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Synthesis of substrates in N-glycan biosythesis Show undefined attributes

authored	[InstanceEdit:749521] Dall'Olio, GM, 2009-11-10
created	[InstanceEdit:446206] Jassal, B, 2009-11-10
dbId	446219
displayName	Synthesis of substrates in N-glycan biosythesis
edited	[InstanceEdit:446206] Jassal, B, 2009-11-10
eventOf	[Pathway:R-HSA-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein - Homo sapiens
hasDiagram	false
hasEHLD	false
hasEvent	[Pathway:R-HSA-446199] Synthesis of dolichyl-phosphate - Homo sapiens [Pathway:R-HSA-446210] Synthesis of UDP-N-acetyl-glucosamine - Homo sapiens [Pathway:R-HSA-446205] Synthesis of GDP-mannose - Homo sapiens [Pathway:R-HSA-162699] Synthesis of dolichyl-phosphate mannose - Homo sapiens [Pathway:R-HSA-480985] Synthesis of dolichyl-phosphate-glucose - Homo sapiens [Pathway:R-HSA-4085001] Sialic acid metabolism - Homo sapiens [Pathway:R-HSA-6787639] GDP-fucose biosynthesis - Homo sapiens
isInDisease	false
isInferred	false
lastUpdatedDate	2023-09-13
literatureReference	[LiteratureReference:507914] Distinct flippases translocate glycerophospholipids and oligosaccharide diphosphate dolichols across the endoplasmic reticulum
maxDepth	3
modified	[InstanceEdit:11108703] Weiser, Joel, 2026-03-16
name	Synthesis of substrates in N-glycan biosythesis
orthologousEvent	[Pathway:R-PFA-446219] Synthesis of substrates in N-glycan biosythesis - Plasmodium falciparum [Pathway:R-DRE-446219] Synthesis of substrates in N-glycan biosythesis - Danio rerio [Pathway:R-DDI-446219] Synthesis of substrates in N-glycan biosythesis - Dictyostelium discoideum [Pathway:R-SCE-446219] Synthesis of substrates in N-glycan biosythesis - Saccharomyces cerevisiae [Pathway:R-SPO-446219] Synthesis of substrates in N-glycan biosythesis - Schizosaccharomyces pombe [Pathway:R-XTR-446219] Synthesis of substrates in N-glycan biosythesis - Xenopus tropicalis [Pathway:R-CFA-446219] Synthesis of substrates in N-glycan biosythesis - Canis familiaris [Pathway:R-RNO-446219] Synthesis of substrates in N-glycan biosythesis - Rattus norvegicus [Pathway:R-MMU-446219] Synthesis of substrates in N-glycan biosythesis - Mus musculus [Pathway:R-SSC-446219] Synthesis of substrates in N-glycan biosythesis - Sus scrofa [Pathway:R-CEL-446219] Synthesis of substrates in N-glycan biosythesis - Caenorhabditis elegans [Pathway:R-DME-446219] Synthesis of substrates in N-glycan biosythesis - Drosophila melanogaster [Pathway:R-GGA-446219] Synthesis of substrates in N-glycan biosythesis - Gallus gallus [Pathway:R-BTA-446219] Synthesis of substrates in N-glycan biosythesis - Bos taurus
releaseDate	2010-06-15
releaseStatus	UPDATED
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:749519] Gagneux, P, 2010-04-16
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-446219
summation	[Summation:507913] Reactions for the synthesis of the small nucleotide-linked s...
updateTrackers	[UpdateTracker:9842343] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v86:[updateIndirectRLE] [UpdateTracker:9784698] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v53:[updateIndirectRLE] [UpdateTracker:9789750] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v37:[updateIndirectRLE] [UpdateTracker:9786899] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v47:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9786709] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v48:[addHasEvent] [UpdateTracker:9785651] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v51:[updateIndirectRLE] [UpdateTracker:9787035] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v46:[modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9783934] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v55:[addHasEvent, updateIndirectRLE] [UpdateTracker:9778167] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v68:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9785494] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v52:[updateIndirectRLE] [UpdateTracker:9782265] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v59:[updateIndirectRLE] [UpdateTracker:9790245] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v34:[modifyText, updateContainedPathway, updateIndirectRLE] [UpdateTracker:9781854] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v60:[updateIndirectRLE] [UpdateTracker:9783741] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v56:[updateContainedPathway] [UpdateTracker:9911012] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v89:[updateContainedPathway, updateIndirectRLE] [UpdateTracker:9787495] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v45:[updateIndirectRLE]

Referrals

(updatedInstance)

[UpdateTracker:9842343] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v86:[updateIndirectRLE]
[UpdateTracker:9784698] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v53:[updateIndirectRLE]
[UpdateTracker:9789750] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v37:[updateIndirectRLE]
[UpdateTracker:9786899] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v47:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9786709] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v48:[addHasEvent]
[UpdateTracker:9785651] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v51:[updateIndirectRLE]
[UpdateTracker:9787035] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v46:[modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9783934] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v55:[addHasEvent, updateIndirectRLE]
[UpdateTracker:9778167] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v68:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9785494] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v52:[updateIndirectRLE]
[UpdateTracker:9782265] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v59:[updateIndirectRLE]
[UpdateTracker:9790245] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v34:[modifyText, updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9781854] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v60:[updateIndirectRLE]
[UpdateTracker:9783741] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v56:[updateContainedPathway]
[UpdateTracker:9911012] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v89:[updateContainedPathway, updateIndirectRLE]
[UpdateTracker:9787495] Update Tracker - [Pathway:446219] Synthesis of substrates in N-glycan biosythesis - v45:[updateIndirectRLE]

(hasEvent)

[Pathway:R-HSA-446193] Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein

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