Reactome | p-Y641-STAT6 dimer [nucleoplasm]

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p-Y641-STAT6 dimer [nucleoplasm] Show undefined attributes

compartment	[Compartment:7660] nucleoplasm
componentOf	[Complex:R-HSA-9976109] MLL1:MEN1:p-Y641-STAT6:p-S243-NFATC2:Notch1,2 Coactivator:GATA3 gene [nucleoplasm] - Homo sapiens [Complex:R-HSA-9977761] GATA3:YY1:ETS1:POU2F1:POU2F2:BATF:p-Y641-STAT6:SATB1:IRF4:SMARCA4:RAD50 gene [nucleoplasm] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-9976117] STAT6, NFATC2 (NFAT1), and NICD1,2 bind the GATA3 gene and cause displacement of repressor complexes (PRC1, RBPJ:NCOR) by activator complexes (MLL1, RBPJ:NICD1,2) - Homo sapiens [Reaction:R-HSA-9977764] GATA3, YY1, ETS1, POU2F1 (OCT1), POU2F2 (OCT2), BATF, SATB1, IRF4, SMARCA4, and STAT6 bind the Locus Control Region (LCR) in the RAD50 gene - Homo sapiens
created	[InstanceEdit:6786277] Jupe, Steve, 2015-07-06
dbId	6786281
displayName	p-Y641-STAT6 dimer [nucleoplasm]
hasComponent	2 × [EntityWithAccessionedSequence:R-HSA-6786279] p-Y641-STAT6 [nucleoplasm]
inDisease	false
inferredTo	[Complex:R-MMU-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Mus musculus [Complex:R-RNO-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Rattus norvegicus [Complex:R-CFA-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Canis familiaris [Complex:R-BTA-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Bos taurus [Complex:R-SSC-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Sus scrofa [Complex:R-DRE-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Danio rerio [Complex:R-XTR-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Xenopus tropicalis [Complex:R-GGA-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Gallus gallus [Complex:R-DME-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Drosophila melanogaster [Complex:R-CEL-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Caenorhabditis elegans [Complex:R-DDI-6786281] p-Y641-STAT6 dimer [nucleoplasm] - Dictyostelium discoideum
isChimeric	false
maxDepth	2
memberOf	[DefinedSet:R-HSA-6788618] p-Y701-STAT1 dimer,p-Y705-STAT3 dimer,p-Y641-STAT6 dimer [nucleoplasm] - Homo sapiens
modified	[InstanceEdit:8879177] Wu, G, 2016-07-15
name	p-Y641-STAT6 dimer
positivelyRegulates	[PositiveGeneExpressionRegulation:R-HSA-6787779] Positive gene expression regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveRegulation:R-HSA-6794002] Positive regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-6794000] Positive gene expression regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveRegulation:R-HSA-6793997] Positive regulation by 'p-Y641-STAT6 dimer [nucleoplasm]'
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6786281

Referrals

(regulator)	[PositiveGeneExpressionRegulation:R-HSA-6787779] Positive gene expression regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveRegulation:R-HSA-6794002] Positive regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveGeneExpressionRegulation:R-HSA-6794000] Positive gene expression regulation by 'p-Y641-STAT6 dimer [nucleoplasm]' [PositiveRegulation:R-HSA-6793997] Positive regulation by 'p-Y641-STAT6 dimer [nucleoplasm]'
(hasMember)	[DefinedSet:R-HSA-6788618] p-Y701-STAT1 dimer,p-Y705-STAT3 dimer,p-Y641-STAT6 dimer [nucleoplasm] [DefinedSet:R-HSA-6788575] p-Y705-STAT3 dimer, p-Y641-STAT6 dimer [nucleoplasm]
(input)	[Reaction:R-HSA-9977764] GATA3, YY1, ETS1, POU2F1 (OCT1), POU2F2 (OCT2), BATF, SATB1, IRF4, SMARCA4, and STAT6 bind the Locus Control Region (LCR) in the RAD50 gene [Reaction:R-HSA-9976117] STAT6, NFATC2 (NFAT1), and NICD1,2 bind the GATA3 gene and cause displacement of repressor complexes (PRC1, RBPJ:NCOR) by activator complexes (MLL1, RBPJ:NICD1,2)
(hasComponent)	[Complex:R-HSA-9976109] MLL1:MEN1:p-Y641-STAT6:p-S243-NFATC2:Notch1,2 Coactivator:GATA3 gene [nucleoplasm] [Complex:R-HSA-9977761] GATA3:YY1:ETS1:POU2F1:POU2F2:BATF:p-Y641-STAT6:SATB1:IRF4:SMARCA4:RAD50 gene [nucleoplasm]
(activeUnit)	[PositiveGeneExpressionRegulation:9976145] Positive gene expression regulation by 'MLL1:MEN1:p-Y641-STAT6:p-S243-NFATC2:Notch1,2 Coactivator:GATA3 gene [nucleoplasm]' [PositiveGeneExpressionRegulation:9977763] Positive gene expression regulation by 'GATA3:YY1:ETS1:POU2F1:POU2F2:BATF:p-Y641-STAT6:SATB1:IRF4:SMARCA4:RAD50 gene [nucleoplasm]'

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