Reactome | CMBL hydrolyses OM to OLMS

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CMBL hydrolyses OM to OLMS Show undefined attributes

authored	[InstanceEdit:6786192] Jassal, Bijay, 2015-07-06
catalystActivity	[CatalystActivity:6786202] hydrolase activity of CMBL [cytosol]
category	transition
compartment	[Compartment:70101] cytosol
created	[InstanceEdit:6786192] Jassal, Bijay, 2015-07-06
dbId	6786190
displayName	CMBL hydrolyses OM to OLMS
edited	[InstanceEdit:6786192] Jassal, Bijay, 2015-07-06
eventOf	[Pathway:R-HSA-211945] Phase I - Functionalization of compounds - Homo sapiens
input	[SimpleEntity:R-ALL-29356] H2O [cytosol] [SimpleEntity:R-ALL-6786175] OM [cytosol]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6786176] Human carboxymethylenebutenolidase as a bioactivating hydrolase of olmesartan medoxomil in liver and intestine
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	CMBL hydrolyses OM to OLMS
orthologousEvent	[Reaction:R-GGA-6786190] CMBL hydrolyses OM to OLMS - Gallus gallus [Reaction:R-XTR-6786190] CMBL hydrolyses OM to OLMS - Xenopus tropicalis [Reaction:R-DRE-6786190] CMBL hydrolyses OM to OLMS - Danio rerio [Reaction:R-SSC-6786190] CMBL hydrolyses OM to OLMS - Sus scrofa [Reaction:R-BTA-6786190] CMBL hydrolyses OM to OLMS - Bos taurus [Reaction:R-CFA-6786190] CMBL hydrolyses OM to OLMS - Canis familiaris [Reaction:R-RNO-6786190] CMBL hydrolyses OM to OLMS - Rattus norvegicus [Reaction:R-MMU-6786190] CMBL hydrolyses OM to OLMS - Mus musculus
output	[SimpleEntity:R-ALL-6786179] diketone [cytosol] [ChemicalDrug:R-ALL-9838649] OLMS [cytosol]
previousReviewStatus	[ReviewStatus:9821384] two stars
releaseDate	2015-12-15
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6797578] D'Eustachio, Peter, 2015-09-14 [InstanceEdit:9853093] D'Eustachio, Peter, 2023-06-24
revised	[InstanceEdit:9842118] D'Eustachio, Peter, 2023-08-18
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6786190
summation	[Summation:6786185] Carboxymethylenebutenolidase homolog (CMBL) is a cytosolic h...
updateTrackers	[UpdateTracker:9842344] Update Tracker - [Reaction:6786190] CMBL hydrolyses OM to OLMS - v86:[add_removeOutput]

Referrals

(updatedInstance)	[UpdateTracker:9842344] Update Tracker - [Reaction:6786190] CMBL hydrolyses OM to OLMS - v86:[add_removeOutput]
(hasEvent)	[Pathway:R-HSA-211945] Phase I - Functionalization of compounds

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