Reactome | FANCD2 deubiquitination by USP1:WDR48

Schema > Reaction > Entries

FANCD2 deubiquitination by USP1:WDR48 Show undefined attributes

authored	[InstanceEdit:419516] Matthews, L, 2009-05-02 17:26:55
catalystActivity	[CatalystActivity:420759] cysteine-type deubiquitinase activity of USP1:WDR48 [nucleoplasm]
category	transition
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:6786172] Orlic-Milacic, Marija, 2015-07-03
dbId	6786171
deleted	[Deleted:6793205] Deletion of instance: 419525 [Deleted:6793362] Deletion of instance: 419552
displayName	FANCD2 deubiquitination by USP1:WDR48
edited	[InstanceEdit:421857] Matthews, L, 2009-05-20 15:51:04
eventOf	[Pathway:R-HSA-6783310] Fanconi Anemia Pathway - Homo sapiens
input	[Complex:R-HSA-6785367] MonoUb:K561,p-T691,S717-FANCD2:MonoUb:K523,p-4S-FANCI:FA Core Complex:ICL-DNA [nucleoplasm]
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:421859] A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
maxDepth	1
modified	[InstanceEdit:10732209] Weiser, Joel, 2026-03-16
name	FANCD2 deubiquitination by USP1:WDR48
orthologousEvent	[Reaction:R-MMU-6786171] FANCD2 deubiquitination by USP1:WDR48 - Mus musculus [Reaction:R-GGA-6786171] FANCD2 deubiquitination by USP1:WDR48 - Gallus gallus [Reaction:R-SSC-6786171] FANCD2 deubiquitination by USP1:WDR48 - Sus scrofa [Reaction:R-BTA-6786171] FANCD2 deubiquitination by USP1:WDR48 - Bos taurus [Reaction:R-CFA-6786171] FANCD2 deubiquitination by USP1:WDR48 - Canis familiaris [Reaction:R-RNO-6786171] FANCD2 deubiquitination by USP1:WDR48 - Rattus norvegicus
output	[Complex:R-HSA-6788397] p-FA Core Complex:ICL-DNA [nucleoplasm] [Complex:R-HSA-6788402] p-FANCD2:p-FANCI [nucleoplasm] 2 × [DefinedSet:R-HSA-68524] Ub [nucleoplasm]
precedingEvent	[Reaction:R-HSA-6785361] Monoubiquitination of FANCD2:FANCI - Homo sapiens
releaseDate	2009-06-24
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:421862] Huang, TT, 2009-05-20 17:48:24 [InstanceEdit:6792505] Fugger, Kasper, 2015-08-20
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6786171
summation	[Summation:419542] The FA pathway is negatively regulated through the USP1:WDR4...
updateTrackers	[UpdateTracker:9780267] Update Tracker - [Reaction:6786171] FANCD2 deubiquitination by USP1:WDR48 - v63:[modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9780267] Update Tracker - [Reaction:6786171] FANCD2 deubiquitination by USP1:WDR48 - v63:[modifyText]
(replacementInstances)	[Deleted:6793205] Deletion of instance: 419525 [Deleted:6793362] Deletion of instance: 419552
(hasEvent)	[Pathway:R-HSA-6783310] Fanconi Anemia Pathway