Reactome | tRNA processing in the nucleus

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tRNA processing in the nucleus Show undefined attributes

authored	[InstanceEdit:6784528] May, Bruce, 2015-06-20
created	[InstanceEdit:6784560] May, Bruce, 2015-06-21
dbId	6784531
displayName	tRNA processing in the nucleus
doi	10.3180/R-HSA-6784531.1
edited	[InstanceEdit:6784528] May, Bruce, 2015-06-20
eventOf	[Pathway:R-HSA-72306] tRNA processing - Homo sapiens
goBiologicalProcess	[GO_BiologicalProcess:588] tRNA processing
hasDiagram	true
hasEHLD	false
hasEvent	[Reaction:R-HSA-5696810] RNase P cleaves the 5' end of pre-tRNA - Homo sapiens [Reaction:R-HSA-5696815] ELAC2 cleaves the 3' end of pre-tRNA - Homo sapiens [Reaction:R-HSA-5696807] TRNT1 polymerizes CCA at the 3' end of pre-tRNA - Homo sapiens [Reaction:R-HSA-5696813] TSEN complex cleaves the intron from pre-tRNA - Homo sapiens [Reaction:R-HSA-5696816] tRNA ligase complex ligates tRNA exons - Homo sapiens [Reaction:R-HSA-6785478] Processed tRNA binds XPOT and RAN:GTP - Homo sapiens [Reaction:R-HSA-6783483] tRNA:XPOT:RAN:GTP translocates from the nucleus to the cytosol - Homo sapiens
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6784559] The pivotal regulatory landscape of RNA modifications [LiteratureReference:6784585] Molecular mechanisms of template-independent RNA polymerization by tRNA nucleotidyltransferases [LiteratureReference:6784565] 3' processing of eukaryotic precursor tRNAs [LiteratureReference:6784563] Have tRNA, will travel [LiteratureReference:6784572] Archaeal/eukaryal RNase P: subunits, functions and RNA diversification [LiteratureReference:6784578] CCA addition to tRNA: implications for tRNA quality control [LiteratureReference:6784545] Recent progress of structural biology of tRNA processing and modification [LiteratureReference:6784534] A story with a good ending: tRNA 3'-end maturation by CCA-adding enzymes [LiteratureReference:6784564] Diversity and roles of (t)RNA ligases [LiteratureReference:6784581] Eukaryotic ribonuclease P: a plurality of ribonucleoprotein enzymes [LiteratureReference:5696703] Human ribonuclease P: subunits, function, and intranuclear localization [LiteratureReference:6784533] tRNA biology charges to the front [LiteratureReference:6785459] Retrograde movement of tRNAs from the cytoplasm to the nucleus in Saccharomyces cerevisiae [LiteratureReference:6785458] Cutting, dicing, healing and sealing: the molecular surgery of tRNA
maxDepth	2
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	tRNA processing in the nucleus
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6790491] Levinger, Louis, 2015-08-10 [InstanceEdit:6792690] Motorin, Yuri, 2015-08-25 [InstanceEdit:6806693] Jarrous, Nayef, 2015-10-24
schemaClass	Pathway
species	[Species:48887] Homo sapiens
stId	R-HSA-6784531
summation	[Summation:6784543] Genes encoding transfer RNAs are transcribed in the nucleus ...

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[Pathway:R-HSA-72306] tRNA processing

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