Reactome | P6C transforms to 2AMAS

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P6C transforms to 2AMAS Show undefined attributes

authored	[InstanceEdit:6783876] Jassal, Bijay, 2015-06-17
category	transition
compartment	[Compartment:5460] mitochondrial matrix [Compartment:17951] peroxisomal matrix
created	[InstanceEdit:6783876] Jassal, Bijay, 2015-06-17
crossReference	[DatabaseIdentifier:12667573] RHEA:25123 [DatabaseIdentifier:9925995] RHEA:25123
dbId	6783883
displayName	P6C transforms to 2AMAS
edited	[InstanceEdit:6783876] Jassal, Bijay, 2015-06-17
eventOf	[Pathway:R-HSA-71064] Lysine catabolism - Homo sapiens
followingEvent	[BlackBoxEvent:R-HSA-9960428] 2AMAS transport from peroxisome to mitochondrial matrix - Homo sapiens
input	[SimpleEntity:R-ALL-193465] H+ [peroxisomal matrix] [SimpleEntity:R-ALL-141343] H2O [peroxisomal matrix] [SimpleEntity:R-ALL-6783877] P6C [peroxisomal matrix]
isChimeric	false
isInDisease	false
isInferred	false
literatureReference	[LiteratureReference:6783884] Lysine metabolism in mammalian brain: an update on the importance of recent discoveries
maxDepth	1
modified	[InstanceEdit:9963584] D'Eustachio, Peter, 2025-08-14
name	P6C transforms to 2AMAS H(+) + H2O + L-1-piperideine-6-carboxylate => (S)-2-amino-6-oxohexanoate
output	[SimpleEntity:R-ALL-9960430] 2AMAS [peroxisomal matrix]
precedingEvent	[Reaction:R-HSA-6783880] PIPOX oxidises PPCA to P6C - Homo sapiens
previousReviewStatus	[ReviewStatus:9821385] four stars
releaseDate	2015-09-22
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:6785241] D'Eustachio, Peter, 2015-06-26 [InstanceEdit:9927660] D'Eustachio, Peter, 2024-11-08 [InstanceEdit:9963585] Hill, David P, 2025-08-14
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-6783883
summation	[Summation:6783882] The saccharopine pathway is the predominant lysine degradati...
updateTrackers	[UpdateTracker:9928515] Update Tracker - [BlackBoxEvent:6783883] P6C transforms to 2AMAS - v91:[removeInput] [UpdateTracker:9964744] Update Tracker - [Reaction:6783883] P6C transforms to 2AMAS - v94:[add_removeOutput, modifyText]

Referrals

(updatedInstance)	[UpdateTracker:9928515] Update Tracker - [BlackBoxEvent:6783883] P6C transforms to 2AMAS - v91:[removeInput] [UpdateTracker:9964744] Update Tracker - [Reaction:6783883] P6C transforms to 2AMAS - v94:[add_removeOutput, modifyText]
(hasEvent)	[Pathway:R-HSA-71064] Lysine catabolism
(precedingEvent)	[BlackBoxEvent:R-HSA-9960428] 2AMAS transport from peroxisome to mitochondrial matrix

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