Reactome | USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]

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USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] Show undefined attributes

catalystActivities	[CatalystActivity:6781799] cysteine-type deubiquitinase activity of USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-6781764] USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1 - Homo sapiens
created	[InstanceEdit:6782815] Jupe, Steve, 2015-06-09
dbId	6782777
displayName	USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]
hasComponent	[DefinedSet:R-HSA-6782776] Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] [EntityWithAccessionedSequence:R-HSA-2173138] USP15 [cytosol]
inDisease	false
includedLocation	[Compartment:876] plasma membrane
inferredTo	[Complex:R-MMU-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Mus musculus [Complex:R-RNO-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Rattus norvegicus [Complex:R-CFA-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Canis familiaris [Complex:R-BTA-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Bos taurus [Complex:R-SSC-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Sus scrofa [Complex:R-DRE-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Danio rerio [Complex:R-XTR-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Xenopus tropicalis [Complex:R-GGA-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Gallus gallus [Complex:R-DME-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Drosophila melanogaster [Complex:R-CEL-6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - Caenorhabditis elegans
isChimeric	false
maxDepth	4
modified	[InstanceEdit:9764675] May, Bruce, 2022-02-13
name	USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-6782777
updateTrackers	[UpdateTracker:9899643] Update Tracker - [Complex:6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - v67:[updateContainedComponent] [UpdateTracker:9903180] Update Tracker - [Complex:6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - v80:[modifyName, updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9899643] Update Tracker - [Complex:6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - v67:[updateContainedComponent] [UpdateTracker:9903180] Update Tracker - [Complex:6782777] USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol] - v80:[modifyName, updateContainedComponent]
(input)	[Reaction:R-HSA-6781764] USP15 deubiquitinates SMAD1,SMAD2,SMAD3, SMAD7:SMURF,KEAP1
(physicalEntity)	[CatalystActivity:6781799] cysteine-type deubiquitinase activity of USP15:Ub-SMAD1,Ub-SMAD2,Ub-SMAD3,,Ub-KEAP1,SMAD7:SMURF2:Ub-TGFBR1 [cytosol]

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